Browse by Advisor

2019

Kurmis, Alexis Anna (2019) Activity of Py-Im Polyamides in Anti-Androgen Resistant Prostate Cancer Models. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HC6V-FV39. https://resolver.caltech.edu/CaltechTHESIS:03182019-112436661

2016

Martinez, Thomas Farid (2016) Investigations of Pyrrole-Imidazole Polyamide Effects on DNA Replication. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9RF5RZ2. https://resolver.caltech.edu/CaltechTHESIS:06292015-212932175

2015

Kang, JeenJoo Sophia (2015) Targeting DNA Repeat Sequences with Py-Im Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z93R0QSQ. https://resolver.caltech.edu/CaltechTHESIS:04052015-200117829

Szablowski, Jerzy Olgierd (2015) Biological Activity of Pyrrole-Imidazole Polyamides in vivo. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9Q23X6D. https://resolver.caltech.edu/CaltechTHESIS:05212015-030950854

2014

Yang, Fei (2014) Antitumor Activity of Py-lm Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/VCN2-H580. https://resolver.caltech.edu/CaltechTHESIS:07302013-124522822

2013

Li, Benjamin Chun Yeung (2013) Synthesis and Biological Studies of DNA-binding Cyclic Py-Im Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/82YX-QB29. https://resolver.caltech.edu/CaltechTHESIS:02282013-171348639

Montgomery, David Church (2013) Improving the Biological Activity of Pyrrole-Imidazole Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/28SH-6Z27. https://resolver.caltech.edu/CaltechTHESIS:04182013-113509606

2011

Muzikar, Katy Ann (2011) Repression of DNA-Binding-Dependent Glucocorticoid Receptor-Mediated Gene Expression. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/FKCV-KP50. https://resolver.caltech.edu/CaltechTHESIS:12142010-165109760

Phillips, John Wilson (2011) Biological Activity of a Py-Im Polyamide Androgen Receptor Antagonist. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MPH7-D492. https://resolver.caltech.edu/CaltechTHESIS:06022011-172257819

2010

Farkas, Michelle Elizabeth (2010) Structural Variations on the Turn Unit of DNA-Binding Hairpin Py-Im Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RVY7-BR84. https://resolver.caltech.edu/CaltechTHESIS:10192009-145249345

2009

Chenoweth, David Michael (2009) Synthesis and Structural Studies of Cyclic Py-Im Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PZEC-VA33. https://resolver.caltech.edu/CaltechETD:etd-04282009-211225

Cohen, Justin Delgado (2009) Programming Protein Patterns on DNA Nanostructures with Pyrrole-Imidazole Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/CZ2K-MJ03. https://resolver.caltech.edu/CaltechETD:etd-11232008-171327

Hsu, Carey Frank (2009) Completion of a Programmable DNA-Binding Small Molecule Library. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PG0R-3X44. https://resolver.caltech.edu/CaltechETD:etd-11032008-191338

Jacobs, Claire Sigrid (2009) Structural Modifications to DNA-Binding Polyamides for Improved Biological Activity in Cell Culture. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HMMN-YW83. https://resolver.caltech.edu/CaltechETD:etd-05272009-161836

Puckett, James William (2009) Microarray and Genome-wide Sequencing Approaches to Characterizing DNA Binding Molecules. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/E3NT-SC46. https://resolver.caltech.edu/CaltechETD:etd-05282009-145527

2008

Nickols, Nicholas George (2008) Endogenous Gene Regulation by DNA Binding Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YH4W-4H67. https://resolver.caltech.edu/CaltechETD:etd-06212007-155330

Stafford, Ryan Leonard (2008) Design of Protein-DNA Dimerizers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PF5M-KF68. https://resolver.caltech.edu/CaltechETD:etd-08232007-154048

Tsai, Sherry Mon-Yue (2008) Alpha-Diaminobutyric Acid-Linked Hairpin Polyamide-Alklylator Conjugates. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3S8Y-YD79. https://resolver.caltech.edu/CaltechETD:etd-10152007-175458

2006

Doss, Raymond Michael (2006) Programmable Oligomers for DNA Recognition. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/F0X3-Q612. https://resolver.caltech.edu/CaltechETD:etd-09202008-110622

2005

Best, Timothy Patrick (2005) Localization of DNA-Binding Polyamides in Living Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MQ0D-8P65. https://resolver.caltech.edu/CaltechETD:etd-10172004-184202

Edelson, Benjamin S. (2005) Nuclear Localization of Polyamide-Fluorescein Conjugates in Cell Culture. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XQYG-DW76. https://resolver.caltech.edu/CaltechETD:etd-03162007-135225

Fechter, Eric James (2005) Design of Sequence-Specific DNA Intercalators. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/d0v0-pb71. https://resolver.caltech.edu/CaltechETD:etd-06052005-164552

Marques, Michael Anthony (2005) The Molecular Recognition of DNA by Novel Heterocycles. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/GHEJ-A648. https://resolver.caltech.edu/CaltechETD:etd-05252005-143409

Poulin-Kerstien, Adam Thomas (2005) DNA-Templated Dimerizations of Minor Groove-Binding Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/em7t-g660. https://resolver.caltech.edu/CaltechETD:etd-05252005-100011

2004

Foister, Shane (2004) Shape Selective Recognition of the DNA Minor Groove by Hairpin Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9WK2-3T81. https://resolver.caltech.edu/CaltechETD:etd-05112004-101833

2002

Nguyen Hackley, Doan Hanh (2002) Allosteric Inhibition of Zinc Finger Proteins by DNA Binding Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NJ2K-H827. https://resolver.caltech.edu/CaltechTHESIS:04262012-135843100

Urbach, Adam Robert (2002) 1:1 Motif for DNA Recognition by β-Alanine Linked Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/V6FD-YQ78. https://resolver.caltech.edu/CaltechETD:etd-05202002-104244

Wang, Clay Chia Chun (2002) Sequence Specific Trapping of Topoisomerase I by Camptothecin Polyamide Conjugates. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/sphn-ma74. https://resolver.caltech.edu/CaltechTHESIS:05012012-101216772

1999

Baird, Eldon Eugene (1999) Solid phase synthesis of DNA-binding small molecules. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/zky0-ha94. https://resolver.caltech.edu/CaltechETD:etd-04282006-113514

Carter, Scott Reynolds (1999) Sequence-specific minor groove binding polyamides : DNA recognition and applications. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JGMJ-YJ95. https://resolver.caltech.edu/CaltechETD:etd-04272006-153748

Szewczyk, Jason W. (1999) Design of ligands for sequence-specific recognition of the minor-major grooves of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/zt1g-kq41. https://resolver.caltech.edu/CaltechETD:etd-04282006-112749

Trauger, John Wesley (1999) Design of DNA-binding polyamides for regulation of gene expression. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Q4HD-PT84. https://resolver.caltech.edu/CaltechETD:etd-04282006-111905

White, Sarah (1999) Recognition of all four Watson-Crick base pairs in the minor groove of DNA by synthetic ligands. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/wxsr-8x37. https://resolver.caltech.edu/CaltechETD:etd-05052006-141420

1998

Greenberg, William Anthony (1998) Design and synthesis of ligands for recognition of the major and minor grooves of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/z2xh-y642. https://resolver.caltech.edu/CaltechETD:etd-04282006-114932

Liberles, David Alan (1998) Sequence specific DNA recognition and bending. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/D0Q8-6128. https://resolver.caltech.edu/CaltechETD:etd-04272006-155123

1996

Cho, Junhyeong (1996) Design of cyclic polyamides for sequence-specific recognition of the minor groove of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ksmz-5b60. https://resolver.caltech.edu/CaltechETD:etd-04272006-161449

Kelly, James J. (1996) Binding site size limitations of imidazole-pyrrole polyamides for recognition in the minor groove of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jc2t-pr07. https://resolver.caltech.edu/CaltechTHESIS:03112014-150124711

Parks, Michelle E. (1996) Sequence-specific recognition of DNA by pyrrole-imidazole hairpin polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4cd1-s277. https://resolver.caltech.edu/CaltechETD:etd-04282006-114140

1995

Best, George C. (1995) Sequence composition and mismatch effects on triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/kj1w-5c31. https://resolver.caltech.edu/CaltechETD:etd-09062007-134504

Hacia, Joseph Gerard (1995) The use of modified oligonucleotides to investigate biological applications for triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/15j7-1b14. https://resolver.caltech.edu/CaltechETD:etd-10122007-074500

Han, Hogyu (1995) Study of RNA structure by affinity cleaving. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fwfk-4p70. https://resolver.caltech.edu/CaltechETD:etd-10052007-081104

Singleton, Scott F. (1995) The thermodynamics of oligonucleotide-directed triple helix formation at single DNA sites. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/382c-fz95. https://resolver.caltech.edu/CaltechETD:etd-10242007-090557

1994

Beal, Peter A. (1994) Recognition of double helical DNA by purine oligonucleotides via triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5bbg-zs22. https://resolver.caltech.edu/CaltechTHESIS:04252013-080541344

Mrksich, Milan (1994) Design of peptides for sequence-specific recognition of the minor groove of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7CWH-FH04. https://resolver.caltech.edu/CaltechETD:etd-09212005-075404

Oakley, Martha G. (1994) Design, synthesis and characterization of sequence-specific DNA-cleaving metalloproteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/35m1-1m12. https://resolver.caltech.edu/CaltechTHESIS:05132013-153337171

Singleton, Jennifer Wales (1994) Affinity Cleavage of Double-Stranded DNA Directed by a RecA Nucleoprotein Filament Containing an Oligonucleotide-EDTA•Fe(II). Master's thesis, California Institute of Technology. doi:10.7907/x3y9-dk45. https://resolver.caltech.edu/CaltechTHESIS:09142018-083120243

1993

Graham, Kenneth Scott (1993) Design and chemical synthesis of a sequence-specific DNA-cleaving metalloprotein: NI (II) GGH-γδ(141-183). Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7xmm-gb60. https://resolver.caltech.edu/CaltechTHESIS:12182012-094906629

1992

Luebke, Kevin J. (1992) Sequence specific nonenzymatic ligation of single- and double-stranded DNA by triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/60d2-7x44. https://resolver.caltech.edu/CaltechTHESIS:09072011-081106540

Povsic, Thomas J. (1992) Oligonucleotide directed sequence specific recognition and alkylation of double helical DNA by triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/krbx-2z47. https://resolver.caltech.edu/CaltechTHESIS:09222011-113738481

Strobel, Scott A. (1992) Site specific cleavage of genomic DNA mediated by triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7TYF-9326. https://resolver.caltech.edu/CaltechTHESIS:09092011-112420199

1991

Koh, Jong Sung (1991) Design of novel bases for recognition of GC base pairs by oligonucleotide-directed triple helix formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9655-mf61. https://resolver.caltech.edu/CaltechETD:etd-11292005-133156

Mack, David Phillip (1991) Design and chemical synthesis of sequence specific DNA cleaving metalloproteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/x5gq-8t63. https://resolver.caltech.edu/CaltechETD:etd-06282007-112041

1990

Griffin, John Hampton (1990) Structure-, stereochemistry-, and metal-regulated DNA binding/cleaving molecules. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fnf1-yc64. https://resolver.caltech.edu/CaltechTHESIS:07302014-102529450

Griffin, Linda Chu-Li (1990) Oligonucleotide-Directed Cleavage of Single- and Double-Stranded DNA by Double and Triple Helix Formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/vsda-zz91. https://resolver.caltech.edu/CaltechETD:etd-06072007-095616

Hanson, James Edward (1990) I. Matrix Isolation of 1,1-Diazenes. II. Distance, Temperature, and Dynamic Solvent Effects on Electron Transfer Reactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1F5A-AC10. https://resolver.caltech.edu/CaltechETD:etd-06072007-131625

Mendel, David (1990) Chemical and Enzymatic Footprinting of Quinoxaline Antibiotics on DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1kmd-qq48. https://resolver.caltech.edu/CaltechETD:etd-06072007-085143

1989

Wade, Warren Stanfield (1989) Sequence Specific Complexation of B DNA at Sites Containing G,C Base Pairs. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9kdn-0y27. https://resolver.caltech.edu/CaltechTHESIS:10242013-102113951

1988

Baker, Brenda Faye (1988) Sequence Specific Cleavage of Double Helical DNA N-Bromoacetyldistamycin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3c0t-vj26. https://resolver.caltech.edu/CaltechTHESIS:01222013-095919666

Iverson, Brent Lee (1988) 1. Nonenzymatic Cleavage of Single-Stranded DNA to Nucleotide Resolution. 2. Novel Base Specific DNA Cleavage Reactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/pd8h-vx39. https://resolver.caltech.edu/CaltechTHESIS:01242013-083723752

Iverson, Sheila Anne (1988) Blue Copper Proteins: Gene Synthesis and Expression. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/z0s5-h938. https://resolver.caltech.edu/CaltechTHESIS:01222013-153725842

Sluka, James P. (1988) Design, Synthesis and Characterization of Sequence Specific DNA Cleaving Agents. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4mj0-ec33. https://resolver.caltech.edu/CaltechTHESIS:03112013-144406216

Youngquist, Robert Scott (1988) Sequence Specific Recognition and Cleavage of DNA by Synthetic Molecules. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/m1pc-hr68. https://resolver.caltech.edu/CaltechTHESIS:03132013-142505168

1987

Dussault, Patrick H. (1987) Approaches to the Total Synthesis of Aplysiatoxin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/zta1-3f55. https://resolver.caltech.edu/CaltechTHESIS:04122019-170707466

Jain, Rakesh (1987) Direct Observation and Reactions of Organic Biradicals Generated from Novel Bicyclic Azoalkanes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/z16r-7e62. https://resolver.caltech.edu/CaltechTHESIS:02252019-123337280

Leland, Burton Alan (1987) Photoinduced Electron Transfer: Synthetic Models of the Primary Processes in Photosynthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ncrh-n123. https://resolver.caltech.edu/CaltechTHESIS:02252019-100631121

1986

Joran, Alvin David (1986) Photochemical Electron Transfer at Fixed Distance: A Synthetic Model of the Photosynthetic Primary Process. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/chrv-qx20. https://resolver.caltech.edu/CaltechTHESIS:11052015-135421366

1984

McElwee-White, Lisa Ann (1984) Theoretical and Experimental Assessment of the Viability of 1,4,6,9-Spiro[4.4]Nonatetrayl as a Reactive Intermediate. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nytz-bf09. https://resolver.caltech.edu/CaltechTHESIS:10262009-151524640

1983

Daub, John Powell (1983) The Total Synthesis of Macrolide Antibiotics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/87f1-5d52. https://resolver.caltech.edu/CaltechTHESIS:09032019-095416829

Krauss, Eric Martin (1983) Conformation and Function of Gramicidin S, A Peptide Antibiotic Which Mediates Phase Transfer of Nucleotides and Nucleic Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/d8tf-3k19. https://resolver.caltech.edu/CaltechTHESIS:10172019-173615812

McGee, Dennis Emmett (1983) Diol Dehydratase: Purification, Structural Characterization, and Mechanism of Action. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xkz2-e227. https://resolver.caltech.edu/CaltechTHESIS:04082021-204133329

Straus, Daniel Albert (1983) Synthesis and Reactivity of Bis(cyclopentadienyl)titanacyclobutanes and Ketene Complexes of Bis(cyclopentadienyl)titanium and Bis(cyclopentadienyl)zirconium. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1jtq-cj35. https://resolver.caltech.edu/CaltechTHESIS:11042019-122031306

1981

Brown-Wensley, Katherine Ann (1981) Formation of Bonds to Carbon at Transition Metal Centers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/sz44-eg97. https://resolver.caltech.edu/CaltechTHESIS:03022018-142501266

Casewit, Carla Jutta (1981) I. Electrophilic Reactions of p-Toluenesulfonyl Azide. II. ¹⁵N and ¹³C Nuclear Magnetic Studies of Aryldiazonium Compounds Effect of Substituent, Solvent and 18-Crown-6. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nyft-yr23. https://resolver.caltech.edu/CaltechETD:etd-01112005-143434

Drew, Horace Rainsford, III (1981) The High Resolution Structure of DNA by Single-Crystal X-Ray Methods. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/vkqm-0f09. https://resolver.caltech.edu/CaltechTHESIS:03062018-111249837

Hardy, Richard Randolph (1981) Studies of the Specificities and Function of Immunoglobulins. I. Relationship Between Structures and Specificity in Dinitrophenyl-Binding Mouse Myeloma Immunoglobulins. II. Effector Function Triggering in Immunoglobulins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/wcn5-3w02. https://resolver.caltech.edu/CaltechTHESIS:05082018-102024886

Herndier, Brian (1981) Activation of Cell Function; Pharmacological Agents Which Degranulate Mast Cells and Cause Skeletal Muscle to Contract. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9txk-fw43. https://resolver.caltech.edu/CaltechTHESIS:03062018-113544116

Koelsch, Peter Martin (1981) Use of Masked Quinones in Organic Synthesis: Efforts Directed Towards the Synthesis of Tropolonoid Natural Products. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/v5ga-5777. https://resolver.caltech.edu/CaltechTHESIS:05082018-144257927

Taber, Terry Ray (1981) The Total Synthesis of A-23187 and Related Enantioselective Aldol Condensations. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xcz4-1016. https://resolver.caltech.edu/CaltechTHESIS:05072018-142839331

Takacs, James Michael (1981) Approaches to Asymmetric Synthesis. The Diastereoselective Alkylations of Chiral Propionamide Enolates. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/f2kf-9406. https://resolver.caltech.edu/CaltechTHESIS:05092018-115015856

1980

Adler, George (1980) NMR Studies of Cooperativity in Hemoglobin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/089e-bj69. https://resolver.caltech.edu/CaltechTHESIS:12112020-012735380

Hinsberg, William Dinan, III (1980) The Synthesis, Spectroscopic Observation and Chemical Reactivity of N-(2,2,6,6-Tetramethylpiperidyl)Ni trene. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3R32-XC97. https://resolver.caltech.edu/CaltechTHESIS:07252016-112114482

1979

Jones, Carol Ruth (1979) The Syntheses and Thermal Decompositions of Six-Membered Cyclic Diacyl Peroxides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/R2WT-EV58. https://resolver.caltech.edu/CaltechETD:etd-08072008-145712

1978

Shippey, Michael Allen (1978) Trimethylsilyl Anions: Stereospecific Deoxygenation of Epoxides and Trimethylsilyldehalogenation of Aryl Halides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/g9fx-wb19. https://resolver.caltech.edu/CaltechTHESIS:01232015-153319101

1977

Hawke, David Harry (1977) Thermal Decomposition of (Presumed) Bismethylene Diazene. Master's thesis, California Institute of Technology. doi:10.7907/2F5K-AV65. https://resolver.caltech.edu/CaltechTHESIS:11242009-081150564