Citation
Taber, Terry Ray (1981) The Total Synthesis of A-23187 and Related Enantioselective Aldol Condensations. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xcz4-1016. https://resolver.caltech.edu/CaltechTHESIS:05072018-142839331
Abstract
A-23187 is a calcium specific ionophore which was isolated from Streptomyces chartreusis. The total synthesis of A-23187 and synthesis of related diacid ionophores are discussed.
[Chemical structure included in scanned thesis' Abstract, p. v.]
The synthetic approach used for A-23187 required stereoselective aldol condensations. In this regard, the development of enantioselective aldol condensations with boron enolates is detailed. The general applications of such condensations are also discussed.
| Item Type: | Thesis (Dissertation (Ph.D.)) | ||||||
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| Subject Keywords: | Chemistry | ||||||
| Degree Grantor: | California Institute of Technology | ||||||
| Division: | Chemistry and Chemical Engineering | ||||||
| Major Option: | Chemistry | ||||||
| Thesis Availability: | Public (worldwide access) | ||||||
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| Defense Date: | 8 October 1980 | ||||||
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| Record Number: | CaltechTHESIS:05072018-142839331 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechTHESIS:05072018-142839331 | ||||||
| DOI: | 10.7907/xcz4-1016 | ||||||
| Default Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 10853 | ||||||
| Collection: | CaltechTHESIS | ||||||
| Deposited By: | Mel Ray | ||||||
| Deposited On: | 08 May 2018 17:40 | ||||||
| Last Modified: | 19 Apr 2021 22:39 |
Thesis Files
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