Browse by Committee Member

2025

Mai, Huanghao (2025) Advancing Structural Analysis with Computational Methods Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4p95-d385. https://resolver.caltech.edu/CaltechTHESIS:07252024-205053475

2024

Orta, Anna Karen (2024) Leveraging the ΦX174 Protein Antibiotic to Study MraY Structure, Function, and Regulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ggr0-0n72. https://resolver.caltech.edu/CaltechTHESIS:06042024-022255958

Saladi, Shyam Madhukar (2024) Some Computer Studies of Membrane Proteins, Molecular Chaperones, and Color. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/40cw-kn70. https://resolver.caltech.edu/CaltechTHESIS:10232023-184021847

2023

Maggiolo, Ailiena Okumura (2023) Crystallographic Studies of Nitrogenase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p232-4w49. https://resolver.caltech.edu/CaltechTHESIS:06062023-051752771

Pinton Tomaleri, Giovani (2023) Structure and Mechanism of the Human ER Membrane Protein Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/e85y-re86. https://resolver.caltech.edu/CaltechTHESIS:06012023-220838845

2022

Abernathy, Morgan Elizabeth (2022) Antibody Targeting of HIV-1 Env: a Structural Perspective. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0p2b-aa45. https://resolver.caltech.edu/CaltechTHESIS:02012022-191225421

Fry, Michelle Yen (2022) Mechanistic Studies of Tail-Anchored Membrane Protein Targeting to the ER. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/b3yj-c572. https://resolver.caltech.edu/CaltechTHESIS:08232021-203647268

Goldberg, Nathaniel Wood (2022) Non-Native Chemistry of Metalloenzymes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6sec-zx89. https://resolver.caltech.edu/CaltechTHESIS:02232022-224045858

Jette, Claudia Angela (2022) Targeting Fusion Proteins of HIV-1 and SARS-CoV-2. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/pxa2-dy41. https://resolver.caltech.edu/CaltechThesis:04282022-192922044

Petrovic, Stefan (2022) Structure and Function of the Human Nuclear Pore Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/g77e-h329. https://resolver.caltech.edu/CaltechTHESIS:05262022-064823923

Zimmer, Matthew Holden (2022) Cotranslational Pulling Forces Alter Outcomes of Protein Synthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p7vk-cf03. https://resolver.caltech.edu/CaltechTHESIS:07232021-171251780

2021

Cohen, Alexander Armand (2021) Developing Multivalent Nanoparticle Vaccines Against Current and Future Viruses. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/r33z-kj46. https://resolver.caltech.edu/CaltechTHESIS:06082021-015935441

Jette, Carina Ivonne (2021) Transition Metal-Catalyzed Enantioselective Alpha Functionalization of Nitrogen and Oxygen-Containing Heterocycles. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/qs4z-3803. https://resolver.caltech.edu/CaltechTHESIS:11192020-190811434

Knight, Anders Matthew (2021) Expanding the Scope of Metalloprotein Families and Substrate Classes in New-to-Nature Reactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7qh5-5130. https://resolver.caltech.edu/CaltechTHESIS:06212020-111155395

Zhou, Dan (2021) Mechanism of Action of a Therapeutic Peptide, Risuteganib, Suggests that Supporting Mitochondrial Function Underlies its Clinical Efficacy in Treating Leading Causes of Blindness. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9kqf-yr35. https://resolver.caltech.edu/CaltechTHESIS:05282021-020006678

2020

Fan, Chengcheng (2020) Structure, Function, and Application of Bacterial ABC Transporters. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5t65-0047. https://resolver.caltech.edu/CaltechTHESIS:06012020-160106726

Wang, Shuai (2020) Co-Translational Protein Targeting and Insertion by SecA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YAQY-3460. https://resolver.caltech.edu/CaltechTHESIS:10022019-105854314

2019

Chio, Un Seng (2019) Mechanistic Bases for Privileged Capture and Unidirectional Targeting of Tail-Anchored Proteins by the Get3 ATPase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/S1CD-5Z42. https://resolver.caltech.edu/CaltechTHESIS:01112019-160835213

Huber, Ferdinand Michael (2019) Molecular Basis for Ribosomal Protein Protection from Cellular Degradation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4S7C-V170. https://resolver.caltech.edu/CaltechTHESIS:05242019-115311540

Hwang-Fu, Yu-Hsien (2019) Dynamic Regulations of Co-Translational Protein Targeting by the Signal Recognition Particle Receptor in E. coli and Human. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/STGW-8V12. https://resolver.caltech.edu/CaltechTHESIS:12122018-102847326

Lee, Jae Ho (2019) Mechanisms of Co-Translational Protein Targeting by Mammalian SRP. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RF8Y-DK59. https://resolver.caltech.edu/CaltechTHESIS:05292019-142906583

Wang, Haoqing (2019) Structure and Dynamics of HIV-1 Env Trimer. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/65VD-VM42. https://resolver.caltech.edu/CaltechTHESIS:02272019-142326751

Yang, Kevin Kaichuang (2019) Probabilistic Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZR4M-K630. https://resolver.caltech.edu/CaltechTHESIS:12222018-173706714

Yu, Helen (2019) Subunit Selective Degradation of WIZ, a Lenalidomide- and Pomalidomide-Dependent Substrate of E3 Ubiquitin Ligase CRL4CRBN. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z7PK-NH81. https://resolver.caltech.edu/CaltechTHESIS:04232019-210733826

Yun, Hyun Gi (2019) Structural and Biochemical Studies of Enzymes in Bacterial Glycobiology. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/VKH3-XX98. https://resolver.caltech.edu/CaltechTHESIS:05292019-144516804

2018

Burke, Kelly Suzanne (2018) Visualizing mRNA Translation in situ in Single Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z92B8W6R. https://resolver.caltech.edu/CaltechTHESIS:07292017-201142545

Marshall, Stephen Sandell (2018) Improvement of Integral Membrane Protein Expression via Optimization of Simulated Integration Efficiency. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9Q23XD3. https://resolver.caltech.edu/CaltechTHESIS:08292017-151537318

Nguyen, Phong Thanh (2018) Structural and Functional Characterization of the Escherichia coli MetNI Methionine Transporter. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/x9ed-9n64. https://resolver.caltech.edu/CaltechTHESIS:04302018-143201092

Niesen, Michiel Jacobus Maria (2018) Coarse-Grained Simulation Approaches for Protein Integration and Translocation via the Sec Translocon. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91N7ZBS. https://resolver.caltech.edu/CaltechTHESIS:04052018-112428695

2017

Lin, Daniel Hanyang (2017) The Architecture of the Nuclear Pore Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98P5XK8. https://resolver.caltech.edu/CaltechTHESIS:06092017-125142341

Vu, Tran Minh Tri (2017) Studies of the N-end Rule Pathway in Bacteria and Mammals. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9668B5J. https://resolver.caltech.edu/CaltechTHESIS:07022016-190718870

Cheung, Sheldon Ting Fong (2017) Discovery and Development of Small-Molecule Modulators for the Sulfation of Glycosaminoglycans and Studying the Role of O-GlcNAc on CREB through Semisynthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9PR7T0K. https://resolver.caltech.edu/CaltechTHESIS:10032016-103410952

Kamajaya, Aron (2017) Structural Study of Piezo Channel, a Unique Family of Eukaryotic Mechanosensitive Channel. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9JQ0Z00. https://resolver.caltech.edu/CaltechTHESIS:07182016-144756449

Mock, Jee Young (2017) The Bag6 Complex: Biological Complexity through Modularity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91C1TXQ. https://resolver.caltech.edu/CaltechTHESIS:06052017-184553539

Morrison, Christine Nichole (2017) Insights into the Mechanism of Biological Nitrogen Fixation through Characterization of the Nitrogenase Molybdenum-Iron Protein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z95B00HX. https://resolver.caltech.edu/CaltechTHESIS:05112017-113214704

Selck, David Anthony (2017) Microfluidics for Molecular Measurements and Quantitative Distributable Diagnostics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9ZC80XT. https://resolver.caltech.edu/CaltechTHESIS:07292016-195927111

2016

Galimidi, Rachel P. (2016) Combating HIV with Novel Antibody Architectures. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9QC01FR. https://resolver.caltech.edu/CaltechTHESIS:06082016-141626444

Rao, Meera (2016) Mechanisms of Regulation and Fidelity in Tail-Anchored Membrane Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9G73BQN. https://resolver.caltech.edu/CaltechTHESIS:05232016-135949451

2015

Gristick, Harry Benjamin (2015) Investigating the Role of the GET3-GET4/GET5 Interaction During Tail-Anchor Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z95718ZD. https://resolver.caltech.edu/CaltechTHESIS:06052015-162319516

Idigo, Chinenye Abiodun (2015) Structural and Biophysical Characterization of Variants of the Mechanosensitive Channel of Large Conductance (MsCL). Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9542KJ3. https://resolver.caltech.edu/CaltechTHESIS:12152014-153232034

2014

Akopian, David (2014) Phospholipids and a Protein-Conducting Channel Regulate Cotranslational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PMBG-Y424. https://resolver.caltech.edu/CaltechTHESIS:05202014-104709210

Brown, Joshua Micah (2014) Investigation of Receptors for the Modulation of Neuronal Growth by Chondroitin Sulfate. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z90G3H45. https://resolver.caltech.edu/CaltechTHESIS:09162013-140043647

Mou, Yun (2014) Computational Design of Self-Assembling Proteins and Protein-DNA Nanowires. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9PG1PPV. https://resolver.caltech.edu/CaltechTHESIS:05232014-201621983

Pfeilsticker, Jessica A. (2014) A Cocktail of Thermally Stable, Chemically Synthesized Capture Agents for the Efficient Detection of Anti-gp41 Antibodies from Human Sera and Techniques. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0FT2-EF04. https://resolver.caltech.edu/CaltechTHESIS:05262014-170142267

Rome, Michael Evan (2014) The Get3 ATPase Drives Unidirectional Targeting of Tail-Anchored Membrane Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DZ068N. https://resolver.caltech.edu/CaltechTHESIS:04162014-173759568

Scott, Caitlin Eileen (2014) Role of Conformational Changes in G Protein-Coupled Receptor Activation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z94747VG. https://resolver.caltech.edu/CaltechTHESIS:05312014-002701930

Sosa Padilla Araujo, Bernardo (2014) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9KP805N. https://resolver.caltech.edu/CaltechTHESIS:05052014-122744794

2013

Chartron, Justin William (2013) The Structure of a Transmembrane Protein Sorting Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QVCV-8A76. https://resolver.caltech.edu/CaltechTHESIS:10012012-155636249

Keller, Gretchen Eva (2013) Phototriggering Nitric Oxide Synthase from Geobacillus stearothermophilus. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HBFQ-8V20. https://resolver.caltech.edu/CaltechTHESIS:02052013-133909189

Nguyen, Thang Xuan (2013) A Study of Protein Targeting Reveals Insights into Mitigating Protein Aggregation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JA4R-TE24. https://resolver.caltech.edu/CaltechTHESIS:06052013-151748060

Oh, Young In (2013) Synthesis and Biological Activity of Anticoagulant Heparan Sulfate Glycopolymers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/E16S-6T52. https://resolver.caltech.edu/CaltechTHESIS:06022013-204012683

Ting, Christina Lei (2013) A Novel Method for Studying Nucleated Pathways in Membranes: Development and Applications for Gene Delivery. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8FTH-8H35. https://resolver.caltech.edu/CaltechTHESIS:08282012-110955629

Zhang, Bin (2013) Sec-facilitated Protein Translocation and Membrane Integration. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6WWV-V190. https://resolver.caltech.edu/CaltechTHESIS:10172012-174905364

2012

Sontz, Pamela Alisa (2012) DNA-mediated Charge Transport in a Biological Context: Cooperation among Metalloproteins to Find Lesions in the Genome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9YT4-7181. https://resolver.caltech.edu/CaltechTHESIS:05242012-110320685

Kedrowski, Sean M. A. (2012) I. Chemical-Scale Studies of Ligand-Gated Ion Channels, and II. Novel Methods for Phosphonate Synthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RQ16-6C44. https://resolver.caltech.edu/CaltechTHESIS:10112011-135016656

Suloway, Christian J. M. (2012) Structural Insights into Tail-Anchored Protein Targeting by Get3. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/AGES-WJ42. https://resolver.caltech.edu/CaltechTHESIS:02282012-151846967

2011

Jaru-Ampornpan, Peera (2011) Post-Translational Membrane Protein Targeting by the Chloroplast Signal Recognition Particle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RDKZ-8094. https://resolver.caltech.edu/CaltechTHESIS:05242011-165030719

Phillips, John Wilson (2011) Biological Activity of a Py-Im Polyamide Androgen Receptor Antagonist. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MPH7-D492. https://resolver.caltech.edu/CaltechTHESIS:06022011-172257819

Shanata, Jai Anand Pattur (2011) Single-Molecule Studies of Ion Channels Expressing Unnatural Amino Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2Y28-RP86. https://resolver.caltech.edu/CaltechTHESIS:06082011-080856211

Van Deventer, James A. (2011) Biophysics and Protein Engineering with Noncanonical Amino Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/VT2B-8B33. https://resolver.caltech.edu/CaltechTHESIS:04272011-162341841

2010

Bray, Jenelle Kiara (2010) The Development and Application of Computational Methods for the Prediction of G Protein-Coupled Receptor Structures. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1655-ES74. https://resolver.caltech.edu/CaltechETD:etd-09032009-105125

Lee, Paul Eulehwann (2010) Activation of Transcription from a Distance: Investigations on the Oxidation of SoxR by DNA-Mediated Charge Transport. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/44P4-C408. https://resolver.caltech.edu/CaltechTHESIS:03192010-175848794

Pribisko Yen, Melanie Anne (2010) Unfolded States of Heme Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WWS3-C929. https://resolver.caltech.edu/CaltechTHESIS:06242011-125949350

2007

Arjara, Gitrada (2007) Refolding a β-Barrel Membrane Protein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4PSM-AS02. https://resolver.caltech.edu/CaltechETD:etd-05292007-061922