Browse by Committee Member

A

Arias, Renee Justine (2018) Examination of Selenium Incorporation and Product Formation in the Nitrogenase FeMo-Cofactor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5WZV-R440. https://resolver.caltech.edu/CaltechTHESIS:05252018-140505343

Akopian, David (2014) Phospholipids and a Protein-Conducting Channel Regulate Cotranslational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PMBG-Y424. https://resolver.caltech.edu/CaltechTHESIS:05202014-104709210

Ariosa, Aileen Renia (2014) Mechanisms of Substrate Selection by the Signal Recognition Particle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/AEDK-0925. https://resolver.caltech.edu/CaltechTHESIS:05302014-103528106

B

Blythe, Emily Elizabeth (2019) Characterization of Adaptor Binding and Substrate Processing by VCP/p97. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9K4M-0C48. https://resolver.caltech.edu/CaltechTHESIS:05222019-125958370

Boekelheide, Nicholas (2013) Quantum Simulation of Enzyme Catalysis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/A27J-Q614. https://resolver.caltech.edu/CaltechTHESIS:06102013-024419372

Butler, Mark Cheiron (2008) Novel Methods for Force-Detected Nuclear Magnetic Resonance. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/S5K2-NH54. https://resolver.caltech.edu/CaltechETD:etd-06112008-065533

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Chio, Un Seng (2019) Mechanistic Bases for Privileged Capture and Unidirectional Targeting of Tail-Anchored Proteins by the Get3 ATPase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/S1CD-5Z42. https://resolver.caltech.edu/CaltechTHESIS:01112019-160835213

Cahn, Jackson Kenai Blender (2016) Engineering, Predicting, and Understanding Nicotinamide Cofactor Specificity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9QV3JJ8. https://resolver.caltech.edu/CaltechTHESIS:01212016-225223309

Chartron, Justin William (2013) The Structure of a Transmembrane Protein Sorting Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QVCV-8A76. https://resolver.caltech.edu/CaltechTHESIS:10012012-155636249

Chaudhuri, Aadel Ahmed (2012) MicroRNAs 155 and 125b Physiologically and Pathologically Regulate Hematopoiesis and Immunity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HFSQ-8278. https://resolver.caltech.edu/CaltechTHESIS:09042011-230002591

Connor, Rebecca Elizabeth (2008) N-Terminal Modification and Codon Reassignment with Non-Canonical Amino Acids in Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ERVA-Q969. https://resolver.caltech.edu/CaltechETD:etd-03052008-065324

D

Duan, Mengtong (Tom) (2024) Expanding Frontiers in Biomedical Imaging and Synthetic Biology: Dynamic Acoustic Reporter Gene Imaging and Ratio-Tuning of Mammalian mRNA Polycistronic Expression. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/avgk-yc71. https://resolver.caltech.edu/CaltechTHESIS:06032024-011201674

D'Espaux, Leopold Daniel (2013) Synthetic Regulation of Eukaryotic Gene Expression by Noncoding RNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9CR5RBP. https://resolver.caltech.edu/CaltechTHESIS:06062013-121826969

F

Fry, Michelle Yen (2022) Mechanistic Studies of Tail-Anchored Membrane Protein Targeting to the ER. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/b3yj-c572. https://resolver.caltech.edu/CaltechTHESIS:08232021-203647268

Fan, Chengcheng (2020) Structure, Function, and Application of Bacterial ABC Transporters. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5t65-0047. https://resolver.caltech.edu/CaltechTHESIS:06012020-160106726

Frazier, Shawnalea Jimee (2012) Optimization of the GluC1/IVM Neuronal Silencing Tool via Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4AGK-FP05. https://resolver.caltech.edu/CaltechTHESIS:05252012-121406958

G

Gristick, Harry Benjamin (2015) Investigating the Role of the GET3-GET4/GET5 Interaction During Tail-Anchor Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z95718ZD. https://resolver.caltech.edu/CaltechTHESIS:06052015-162319516

Geil, Wendy Mercer (2012) Regulation of Wild-Type and Mutant p53 through DNA-mediated Charge Transport. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0NVZ-QC23. https://resolver.caltech.edu/CaltechTHESIS:10062011-140224145

Gleitsman, Kristin Rule (2010) Chemical-Scale Studies of the Nicotinic Acetylcholine Receptor: Insights from Amide-to-Ester Backbone Mutagenesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZYZF-9E22. https://resolver.caltech.edu/CaltechTHESIS:05102010-211900670

H

Hazu, Masami (2025) Mechanistic Studies of Membrane Protein Biogenesis at the ER and Mitochondria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/snc5-jf69. https://resolver.caltech.edu/CaltechTHESIS:02082025-232945882

Hsieh, Hao-Hsuan (2023) Coordination Between Mammalian Nascent Protein Targeting and Cotranslational Chaperones. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/x61p-vf31. https://resolver.caltech.edu/CaltechTHESIS:07252022-075028264

Huang, Xiawei (2021) Molecular Function and Regulation of Aub Arginine Methylation in the piRNA Pathway. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5734-db78. https://resolver.caltech.edu/CaltechTHESIS:05192021-055633048

Hwang-Fu, Yu-Hsien (2019) Dynamic Regulations of Co-Translational Protein Targeting by the Signal Recognition Particle Receptor in E. coli and Human. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/STGW-8V12. https://resolver.caltech.edu/CaltechTHESIS:12122018-102847326

Hwang, Kiwook (2013) Biotechnologies for Cancer Diagnostics: Cell Sorting, Protein Analysis and Imaging of Cellular Metabolism. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z6DN-0483. https://resolver.caltech.edu/CaltechTHESIS:06072013-111912342

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Jarman, John Bryce (2019) Chemical Tools for the Control of Biological Systems. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MV3V-2R09. https://resolver.caltech.edu/CaltechTHESIS:06032019-100329207

Jaru-Ampornpan, Peera (2011) Post-Translational Membrane Protein Targeting by the Chloroplast Signal Recognition Particle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RDKZ-8094. https://resolver.caltech.edu/CaltechTHESIS:05242011-165030719

K

Kreamer, Naomi N. (2015) Ferrous Iron Sensing and Responding in Pseudomonas aeruginosa. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DN4324. https://resolver.caltech.edu/CaltechTHESIS:03092015-135659710

Kolawa, Natalie J. (2013) Proteomic Analysis of the Cdc48/Ubx Network Identifies a Role for Ubx2 in the Regulation of Lipid Biosynthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/FN9G-KV67. https://resolver.caltech.edu/CaltechTHESIS:05282013-142345187

Krishnamurthy, Chithra (2013) Chemical Probes to Study Fucosylated Glycans. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z99021SG. https://resolver.caltech.edu/CaltechTHESIS:06052013-123658997

L

Luo, Yicheng (2023) Maternally Inherited siRNAs Initiate piRNA Cluster Formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/f2nh-8w08. https://resolver.caltech.edu/CaltechTHESIS:11042022-055503832

Lee, Jae Ho (2019) Mechanisms of Co-Translational Protein Targeting by Mammalian SRP. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RF8Y-DK59. https://resolver.caltech.edu/CaltechTHESIS:05292019-142906583

Liang, JingXin (2018) Interrogating the Structural Landscape of Malaria Biomarkers with Epitope Targeted Peptide Capture Agents. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/rxtr-6152. https://resolver.caltech.edu/CaltechTHESIS:06112018-181603942

Lin, Daniel Hanyang (2017) The Architecture of the Nuclear Pore Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98P5XK8. https://resolver.caltech.edu/CaltechTHESIS:06092017-125142341

Lee, Toni Marie (2014) Computationally-Guided Thermostabilization of the Primary Endoglucanase from Hypocrea jerorina for Cellulosic Biofuel Production. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9S180G0. https://resolver.caltech.edu/CaltechTHESIS:11172013-001549340

Loson, Oliver Calvin (2014) Regulation of Mitochondrial Division by the Drp1 Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/J23G-KQ18. https://resolver.caltech.edu/CaltechTHESIS:05072014-160207088

Lu, Ying Ying (2014) Revealing, Illuminating, and Modifying Proteins in Human Diseases using Noncanonical Amino Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NPBC-3N67. https://resolver.caltech.edu/CaltechTHESIS:08232013-210427528

Limapichat, Walrati (2013) Probing the Roles of Receptor Structure, Drug-Receptor Interactions, and Receptor Crosstalk in Ligand-Gated Ion Channel Function. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YPMW-9E79. https://resolver.caltech.edu/CaltechTHESIS:11052012-192506907

Link, Aaron James (2006) Azide-Bearing Amino Acids in Protein Engineering and Proteomic Profiling. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XXA2-5K11. https://resolver.caltech.edu/CaltechETD:etd-09132005-120123

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Marshall, Stephen Sandell (2018) Improvement of Integral Membrane Protein Expression via Optimization of Simulated Integration Efficiency. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9Q23XD3. https://resolver.caltech.edu/CaltechTHESIS:08292017-151537318

Mock, Jee Young (2017) The Bag6 Complex: Biological Complexity through Modularity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91C1TXQ. https://resolver.caltech.edu/CaltechTHESIS:06052017-184553539

Martinez, Thomas Farid (2016) Investigations of Pyrrole-Imidazole Polyamide Effects on DNA Replication. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9RF5RZ2. https://resolver.caltech.edu/CaltechTHESIS:06292015-212932175

Mosadeghi, Ruzbeh (2015) Mechanistic Dissection of the Cop9 Signalosome’s Deneddylation Activity on Cullin-RING Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9P26W3G. https://resolver.caltech.edu/CaltechTHESIS:05312015-231120184

N

Nguyen, Phong Thanh (2018) Structural and Functional Characterization of the Escherichia coli MetNI Methionine Transporter. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/x9ed-9n64. https://resolver.caltech.edu/CaltechTHESIS:04302018-143201092

Niesen, Michiel Jacobus Maria (2018) Coarse-Grained Simulation Approaches for Protein Integration and Translocation via the Sec Translocon. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91N7ZBS. https://resolver.caltech.edu/CaltechTHESIS:04052018-112428695

Nguyen, Thang Xuan (2013) A Study of Protein Targeting Reveals Insights into Mitigating Protein Aggregation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JA4R-TE24. https://resolver.caltech.edu/CaltechTHESIS:06052013-151748060

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Page, Katharine-Rose (2024) Using Functional Genomics to Characterize Biogenesis and Quality Control Pathways in the Mammalian ER. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4c7k-yw62. https://resolver.caltech.edu/CaltechTHESIS:11062023-233057820

Petrovic, Stefan (2022) Structure and Function of the Human Nuclear Pore Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/g77e-h329. https://resolver.caltech.edu/CaltechTHESIS:05262022-064823923

Pierce, Nathan William (2012) Sequential Processivity and CAND1 Regulate SCF Ubiquitin Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ME1H-AK32. https://resolver.caltech.edu/CaltechTHESIS:11282011-135435821

Privett, Heidi Kathleen (2009) An Iterative Approach to de novo Computational Enzyme Design and the Successful Application to the Kemp Elimination. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1402-XZ32. https://resolver.caltech.edu/CaltechETD:etd-05272009-091024

R

Reichermeier, Kurt Michael (2020) Quantitative Characterization of Composition and Regulation of Cullin-RING Ubiquitin Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0WX7-2Q56. https://resolver.caltech.edu/CaltechTHESIS:12122019-091017133

Rienzo, Matthew (2017) Non-Canonical Amino Acids As Biochemical Probes of Ligand-Gated Ion Channel Structure and Function. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9G44N8W. https://resolver.caltech.edu/CaltechTHESIS:09022016-105040371

Rao, Meera (2016) Mechanisms of Regulation and Fidelity in Tail-Anchored Membrane Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9G73BQN. https://resolver.caltech.edu/CaltechTHESIS:05232016-135949451

Rojansky, Rebecca Bloom (2016) A Core Mitophagic Machinery Promotes Selective Degradation of Paternal Mitochondria in Mouse Embryos and MEF Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z96Q1V75. https://resolver.caltech.edu/CaltechTHESIS:04292016-193643737

Rome, Michael Evan (2014) The Get3 ATPase Drives Unidirectional Targeting of Tail-Anchored Membrane Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DZ068N. https://resolver.caltech.edu/CaltechTHESIS:04162014-173759568

Rogers, Claude Joseph (2013) Discovery of New Roles for Chondroitin Sulfate in Neurotrophin Signaling and Retinotopic Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9N58JCD. https://resolver.caltech.edu/CaltechTHESIS:01272013-150337805

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Shafaat, Oliver Syed (2016) Temporal Control of Ion Channel Activation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98P5XGX. https://resolver.caltech.edu/CaltechTHESIS:05122016-095434020

Scott, Caitlin Eileen (2014) Role of Conformational Changes in G Protein-Coupled Receptor Activation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z94747VG. https://resolver.caltech.edu/CaltechTHESIS:05312014-002701930

Sosa Padilla Araujo, Bernardo (2014) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9KP805N. https://resolver.caltech.edu/CaltechTHESIS:05052014-122744794

Shemorry, Anna (2013) Studies of the N-End Rule Pathway in Saccharomyces cerevisiae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/09SW-FR88. https://resolver.caltech.edu/CaltechTHESIS:01282013-132123935

Shen, Kuang (2013) Novel Roles of the SRP RNA in Co-Translational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NWWW-0867. https://resolver.caltech.edu/CaltechTHESIS:05292013-215935625

Song, Hang (2012) Recognition of Nucleic Acid Mismatches by Luminescent Ruthenium Complexes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4TM6-BR89. https://resolver.caltech.edu/CaltechTHESIS:11072011-185116656

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Vu, Tran Minh Tri (2017) Studies of the N-end Rule Pathway in Bacteria and Mammals. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9668B5J. https://resolver.caltech.edu/CaltechTHESIS:07022016-190718870

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Wang, Jingzhou (2021) CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p0kj-9d56. https://resolver.caltech.edu/CaltechTHESIS:05282021-080632319

Wang, Shuai (2020) Co-Translational Protein Targeting and Insertion by SecA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YAQY-3460. https://resolver.caltech.edu/CaltechTHESIS:10022019-105854314

Wadas, Brandon Christopher (2016) Biochemical and Genetic Studies of the N-End Rule Pathway in Yeast and Mammals. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91V5BZQ. https://resolver.caltech.edu/CaltechTHESIS:06022016-162251299

Wang, Connie Yuan-Ying (2016) Understanding Co-Translational Protein Targeting and Lithium Dendrite Formation through Free Energy Simulations and Coarse-Grained Models. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z97H1GHF. https://resolver.caltech.edu/CaltechTHESIS:05232016-092808469

Webster, Alexandre (2015) Mechanisms of Transposable Element Repression by Piwi Proteins in the piRNA Pathway of Drosophila Germ Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9WQ01RS. https://resolver.caltech.edu/CaltechTHESIS:05112015-230250866

Wang, Andrew Chih-Kae (2015) Investigating the Role of O-GlcNAc Glycosylation in Neurodegeneration. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z97W695K. https://resolver.caltech.edu/CaltechTHESIS:06032015-135024245

Y

Yang, Chien-I (2023) Mechanism and Function of Nascent Protein Modification in Bacteria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/qhz7-a383. https://resolver.caltech.edu/CaltechTHESIS:07032022-182356199

Yu, Helen (2019) Subunit Selective Degradation of WIZ, a Lenalidomide- and Pomalidomide-Dependent Substrate of E3 Ubiquitin Ligase CRL4CRBN. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z7PK-NH81. https://resolver.caltech.edu/CaltechTHESIS:04232019-210733826

Yun, Hyun Gi (2019) Structural and Biochemical Studies of Enzymes in Bacterial Glycobiology. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/VKH3-XX98. https://resolver.caltech.edu/CaltechTHESIS:05292019-144516804

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Zhu, Zikun (2024) Spatiotemporal Regulation of Nascent Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ybz3-4m48. https://resolver.caltech.edu/CaltechTHESIS:05302024-023258565

Zhang, Ruijie (2019) Engineering Heme Proteins for Olefin and Carbon−Hydrogen Bond Functionalization Reactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2076-CX23. https://resolver.caltech.edu/CaltechTHESIS:03102019-234035587

Zhang, Xin (2010) Multistate GTPases Control Cotranslational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/28HP-FJ94. https://resolver.caltech.edu/CaltechTHESIS:05272010-004616557