Browse by Committee Member

2022

MacArdle, Siobhán Gaustad (2022) Analytical Chemistry Investigations Toward Understanding the Mechanism of Nitrogenase from Azotobacter vinelandii and the Role of the 4Fe-4S Cluster of Dna2 from Saccharomyces cerevisiae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/afrw-sx78. https://resolver.caltech.edu/CaltechTHESIS:05252022-173757484

2019

Kurmis, Alexis Anna (2019) Activity of Py-Im Polyamides in Anti-Androgen Resistant Prostate Cancer Models. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HC6V-FV39. https://resolver.caltech.edu/CaltechTHESIS:03182019-112436661

2018

Bartels, Phillip Leon (2018) Elucidating the Role of [4Fe4S] Clusters in DNA Replication and Repair Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9H1307G. https://resolver.caltech.edu/CaltechTHESIS:03012018-094939210

Letsou, William Peter (2018) Noncommutative Biology: Sequential Regulation of Complex Networks and Connected Matter. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9B5E-F105. https://resolver.caltech.edu/CaltechTHESIS:05292018-192944407

2017

Liu, Raymond (2017) Mechanisms of Drp1 Recruitment to Mitochondria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z99Z92ZF. https://resolver.caltech.edu/CaltechTHESIS:05312017-190514797

2016

Martinez, Thomas Farid (2016) Investigations of Pyrrole-Imidazole Polyamide Effects on DNA Replication. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9RF5RZ2. https://resolver.caltech.edu/CaltechTHESIS:06292015-212932175

Pan, Dorothy Weichi (2016) Development of a Cationic Mucic Acid Polymer-Based Nanoparticle siRNA Delivery System. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9VM497J . https://resolver.caltech.edu/CaltechTHESIS:05092016-155820873

Segal, Helen Muriel (2016) Electrochemical Methods to Study Iron-Sulfur Cluster Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z92Z13HT. https://resolver.caltech.edu/CaltechTHESIS:05252016-131059745

2015

Ahmed, Alysia Ashley (2015) Structural Characterization of Pro-inflammatory and Anti-inflammatory Immunoglobulin G Fc Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9GT5K33. https://resolver.caltech.edu/CaltechTHESIS:05292015-064617250

Goldberg, Mark David (2015) Development of Microfluidic Devices with the Use of Nanotechnology to Aid in the Analysis of Biological Systems Including Membrane Protein Separation, Single Cell Analysis, and Genetic Markers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9P848V6. https://resolver.caltech.edu/CaltechTHESIS:06022015-150554177

2014

Mui, Timothy Paul (2014) Expanding the Repertoire of DNA-Mediated Signaling in DNA Repair. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WXQM-CJ32. https://resolver.caltech.edu/CaltechTHESIS:09102013-094001578

Rome, Michael Evan (2014) The Get3 ATPase Drives Unidirectional Targeting of Tail-Anchored Membrane Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DZ068N. https://resolver.caltech.edu/CaltechTHESIS:04162014-173759568

2013

Montgomery, David Church (2013) Improving the Biological Activity of Pyrrole-Imidazole Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/28SH-6Z27. https://resolver.caltech.edu/CaltechTHESIS:04182013-113509606

Shemorry, Anna (2013) Studies of the N-End Rule Pathway in Saccharomyces cerevisiae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/09SW-FR88. https://resolver.caltech.edu/CaltechTHESIS:01282013-132123935

Shen, Kuang (2013) Novel Roles of the SRP RNA in Co-Translational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NWWW-0867. https://resolver.caltech.edu/CaltechTHESIS:05292013-215935625

2011

Fortini, Barbara Karmen Kraatz (2011) Biochemical and Genetic Studies of Genomic Stability. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZH26-B677. https://resolver.caltech.edu/CaltechTHESIS:05172011-123048725

Gomez, Tara Adele (2011) Mutational Analysis of Ubiquitin Shuttle Receptor Docking Sites on the 26S Proteasome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/K9K3-0105. https://resolver.caltech.edu/CaltechTHESIS:05232011-170710428

Phillips, John Wilson (2011) Biological Activity of a Py-Im Polyamide Androgen Receptor Antagonist. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MPH7-D492. https://resolver.caltech.edu/CaltechTHESIS:06022011-172257819

2010

Farkas, Michelle Elizabeth (2010) Structural Variations on the Turn Unit of DNA-Binding Hairpin Py-Im Polyamides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RVY7-BR84. https://resolver.caltech.edu/CaltechTHESIS:10192009-145249345

Gold, Daniel A. (2010) Molecular Characterization of the Dbf4/Drf1-Dependent Kinase (DDK) and the DNA Replication Checkpoint Mediator Claspin in Xenopus Egg Extracts. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XG90-5475. https://resolver.caltech.edu/CaltechTHESIS:10232009-160656505

Lee, Paul Eulehwann (2010) Activation of Transcription from a Distance: Investigations on the Oxidation of SoxR by DNA-Mediated Charge Transport. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/44P4-C408. https://resolver.caltech.edu/CaltechTHESIS:03192010-175848794

Ramírez-Lugo, Juan S. (2010) The Activation of ATR in Response to Double-Stranded DNA Breaks. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EG9Z-0H60. https://resolver.caltech.edu/CaltechTHESIS:05262010-155732939

Wawrousek, Karen Elizabeth (2010) Contributions of Dna2 and the Tim/Tipin Complex to Genomic Stability. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QYSH-WH15. https://resolver.caltech.edu/CaltechTHESIS:01032010-225423037

2009

Gama, Cristal Ivette (2009) Understanding the Chemical Basis of Neuronal Development and Communication: I. The Role of Fucose α(1-2) Galactose Carbohydrates in Neuronal Growth. II. Structure-Function Analysis of Chondroitin Sulfate in the Brain. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/CDGH-MJ49. https://resolver.caltech.edu/CaltechETD:etd-10302008-123855

Rodriguez, Erik Ali (2009) In Vivo Incorporation of Multiple Unnatural Amino Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9H38-9661. https://resolver.caltech.edu/CaltechETD:etd-01122009-153110

2008

Win, Maung Nyan (2008) Engineering RNA Devices for Gene Regulation, Biosensing, and Higher-Order Cellular Information Processing. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/H6J4-P729. https://resolver.caltech.edu/CaltechETD:etd-05282008-142750

Zid, Brian Matthew (2008) Translational Control Mediates Lifespan Extension Due to Dietary Restriction in Drosophila. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8DZY-WB19. https://resolver.caltech.edu/CaltechETD:etd-02052008-020618

2007

Heo, Jiyoung (2007) Computational Studies of Orphan G Protein-Coupled Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/rmmr-sj52. https://resolver.caltech.edu/CaltechETD:etd-11102006-144154

Revilla-i-Domingo, Roger (2007) CIS-Regulatory Analysis of the Sea Urchin Delta Gene: Validating the Architecture of the Gene Regulatory Network Model for Early Micromere Lineage Specification. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/G9GQ-H097. https://resolver.caltech.edu/CaltechETD:etd-06042007-145414

2006

Cope, Gregory Allan (2006) Regulation of SCF Ubiquitin Ligases by Jab1/Csn5 and the Cop9 Signalosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/43JP-NQ47. https://resolver.caltech.edu/CaltechETD:etd-07222005-141530

Marcus, Joshua Scott (2006) Single Mammalian Cell Gene Expression Analysis Using Microfluidics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/M3GA-PT31. https://resolver.caltech.edu/CaltechETD:etd-06282006-103230

2005

Hall, Spencer Eugene (2005) Development of a Structure Prediction Method for G-Protein Coupled Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JN28-5F55. https://resolver.caltech.edu/CaltechETD:etd-06012005-235052

Peng, Joyce Yaochun (2005) Structure and Function Prediction of Human Muscarinic Acetylcholine Receptor 1, Cation-π Studies, and Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XVJR-RN32. https://resolver.caltech.edu/CaltechETD:etd-05312005-114949

2004

Trabanino, Rene Jouvanni (2004) Prediction of Structure, Function, and Spectroscopic Properties of G-Protein-Coupled Receptors: Methods and Applications. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/VHED-4063. https://resolver.caltech.edu/CaltechETD:etd-05202004-174324

2003

Cheng, Timothy Casey (2003) Investigations into the Enzymology and Biotechnology of the Hyperthermophilic Carboxypeptidase (PfuCP) from the Archaeon Pyrococcus furiosus. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/R8WE-R336. https://resolver.caltech.edu/CaltechETD:etd-05272003-203637

2002

Choe, Wonchae (2002) Biochemical and Biological in vivo Functions of Dna2p in Saccharomyces cerevisiae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/P30H-JP90. https://resolver.caltech.edu/CaltechTHESIS:04252012-093049065

Du, Fangyong (2002) Allosteric Activation of the Ubiquitin ligase UBR 1 by Short Peptides: Molecular Mechanisms and Physiological Functions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/S3VT-0641. https://resolver.caltech.edu/CaltechTHESIS:02232012-110128910

2001

Chi, Yong (2001) Negative Regulation of Transcription Factors by Srb10 Cyclin-Dependent Kinase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/tb1q-fz89. https://resolver.caltech.edu/CaltechTHESIS:03072014-113238525

Fang, Xiangdong (2001) Developmentally Regulated Transcription Factors in Drosophila melanogaster. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/h17r-qa60. https://resolver.caltech.edu/CaltechTHESIS:03182014-110657424

Lyapina, Svetlana Anatol'Evna (2001) Characterization of the Human SCF Ubiquitin Ligases - Structure, Function, and Regulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/apdy-3d30. https://resolver.caltech.edu/CaltechTHESIS:03072014-090536401

1999

Kim, Chang Hee (1999) Site-Specific Chemical Modification and Crosslinking Studies of U6 snRNA in the Yeast spliceosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/cfw0-z473. https://resolver.caltech.edu/CaltechTHESIS:01092024-222740445

Yu, Bo (1999) An engineered mutant of G protein [alpha] subunit that binds xanthine nucleotide and not guanine nucleotide. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/K78Q-9K42. https://resolver.caltech.edu/CaltechETD:etd-06172008-140047

1995

Han, Hogyu (1995) Study of RNA structure by affinity cleaving. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fwfk-4p70. https://resolver.caltech.edu/CaltechETD:etd-10052007-081104

1992

Kurur, Narayanan Damodaran (1992) I. Quantum-mechanical chemical exchange. II. NMR of semiconductors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0TQK-G720. https://resolver.caltech.edu/CaltechTHESIS:09022011-090934651

1990

Griffin, Linda Chu-Li (1990) Oligonucleotide-Directed Cleavage of Single- and Double-Stranded DNA by Double and Triple Helix Formation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/vsda-zz91. https://resolver.caltech.edu/CaltechETD:etd-06072007-095616

Hardy, Winters Reef (1990) The characterization and processing of the nonstructural proteins of Sindbis virus. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/gk9d-5371. https://resolver.caltech.edu/CaltechETD:etd-06082007-084319

Kibbe, Warren Alden (1990) A Detailed Analysis of Transcriptional Regulators Affecting the Saccharomyces cerevisiae Heat-shock Gene SSA1. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fraq-3065. https://resolver.caltech.edu/CaltechTHESIS:07242014-161229419

Mendel, David (1990) Chemical and Enzymatic Footprinting of Quinoxaline Antibiotics on DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1kmd-qq48. https://resolver.caltech.edu/CaltechETD:etd-06072007-085143

1989

Healey, William Joseph (1989) The Structural Basis of Enzyme Catalysis: Mutagenesis of β-lactamase at Ala 172, Glu 166, and Ala 237. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/t2g7-x074. https://resolver.caltech.edu/CaltechETD:etd-05212007-133513

Ma, Doreen (1989) Regulatory Elements in ColE1 DNA Replication in Escherichia coli. Mutants of Saccharomyces cerevisiae DNA Polymerase I Resistant to Nucleotide Analogs: dNTP Binding Site Definition. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5b4k-wx16. https://resolver.caltech.edu/CaltechETD:etd-05222007-091103

Selman, Mary (1989) Preparation and Characterization of and Intramolecular Electron Transfer in a Pentaammineruthenium Derivative of Candida krisei Cytochrome c. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/hpxj-n706. https://resolver.caltech.edu/CaltechTHESIS:08262013-151906759

Sweder, Kevin Scot (1989) Isolation and Characterization of Proteins that Bind to Yeast Origins of DNA Replication. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/d0tj-k332. https://resolver.caltech.edu/CaltechTHESIS:08232013-141734040

Vijayraghavan, Usha (1989) A Genetic and Biochemical Analysis of pre-mRNA Splicing in Saccharomyces cerevisiae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/cxmk-nj42. https://resolver.caltech.edu/CaltechTHESIS:10172013-115606044

Wittrup, Karl Dane (1989) Plasmid Propagation in the Yeast Saccharomyces cerevisiae: Flow Cytometry Studies and Segregated Modeling. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/KQYB-CX46. https://resolver.caltech.edu/CaltechETD:etd-02212007-131607

1988

Antypas, William George, Jr. (1988) Nuclear Magnetic Resonance Studies of Biological Systems. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/j4ep-gn92. https://resolver.caltech.edu/CaltechTHESIS:01182013-100334158

Da Silva, Nancy Anderson (1988) Host-Plasmid Interactions and Regulation of Cloned Gene Expression in Recombinant Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/pze3-dp83. https://resolver.caltech.edu/CaltechETD:etd-11062007-104408

Hu, Mickey ChienTsung (1988) I. The E. coli Lac Operator-Repressor System is Functional for Control of Gene Expression in Animal Cells. II. Molecular Cloning and Characterization of the Mouse Skeletal Muscle (α) Actin Gene. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2a59-9p43. https://resolver.caltech.edu/CaltechTHESIS:01232013-085319311

Korber, Bette Tina Marie (1988) Regulation of Class I Genes by Interferons. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/FWT2-VC76. https://resolver.caltech.edu/CaltechETD:etd-01252005-085241

Mayo, Stephen Leon (1988) Electron Transfer in Structurally Engineered Metalloproteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YJKW-3133. https://resolver.caltech.edu/CaltechETD:etd-04292004-095332

Perez, Dianne Marie (1988) Structure-Function Studies of Serine Hydrolases: Synthesis of a Gene for α-Lytic Protease and the Purification and Characterization of a Mutant β-Lactamase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/brjj-5n58. https://resolver.caltech.edu/CaltechTHESIS:03182013-143408752

1986

Seo, Jin-Ho (1986) Investigations of Plasmid-Host Cell Interactions in Recombinant Escherichia coli Populations. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RGTN-X895. https://resolver.caltech.edu/CaltechETD:etd-03102008-104251

1985

Martin, Craig Timothy (1985) The Structures of CuA and Cytochrome a in Cytochrome c Oxidase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/eft1-pp43. https://resolver.caltech.edu/CaltechTHESIS:04052019-144431487

Masters, Jeffrey Nelson (1985) The Organization and Expression of the Human Dihydrofolate Reductase Gene in Methotrexate-Resistant and Methotrexate-Sensitive Cell Lines. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jaa8-jx74. https://resolver.caltech.edu/CaltechTHESIS:01312019-142248860

1984

Ikeda, Richard Alan (1984) I. Bismethidium Intercalators: The Binding of Nucleic Acids and II. Experiments in the Design of Site Specific DNA Cleaving Agents. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xp0y-6y73. https://resolver.caltech.edu/CaltechTHESIS:11122018-122020454

Kaiser, Robert James, Jr. (1984) Nuclear Magnetic Resonance and Kinetic Studies of the Catalytic Mechanism of the Serine Proteases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xg11-xg51. https://resolver.caltech.edu/CaltechTHESIS:11162018-115223569

Kuo, Chia-lam (1984) Use of Temperature Sensitive Mutants to Study Yeast DNA Replication. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/gekb-yq20. https://resolver.caltech.edu/CaltechTHESIS:11212018-100547724

Van Dyke, Michael W. (1984) MPE•Fe(II) Footprinting: Drug Binding Sites on Native DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/vy36-rq29. https://resolver.caltech.edu/CaltechTHESIS:12052018-113900386

1983

Becker, Nancy Newton (1983) ¹⁵N Nuclear Magnetic Resonance Studies of the Liver Alcohol Dehydrogenase-NAD⁺-Pyrazole Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nnx8-q333. https://resolver.caltech.edu/CaltechTHESIS:09262018-161343127

1982

Conner, Benjamin Norman (1982) Iodo-CCGG: A Single Crystal Structure of A-DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3t68-dc11. https://resolver.caltech.edu/CaltechTHESIS:05142018-150830492

1981

Miller, James Arthur (1981) Studies on Ligand Binding to the Histrionicotoxin and the Agonist Binding Sites of Membrane Bound Acetylcholine Receptor from Torpedo californica. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/wd5n-dn51. https://resolver.caltech.edu/CaltechTHESIS:03132018-105051819

Sargent, Thomas Dean (1981) The Rat Serum Albumin Gene. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/22x8-g069. https://resolver.caltech.edu/CaltechTHESIS:02172017-094958964