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Items where Option is "Biochemistry and Molecular Biophysics"

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    • Biochemistry and Molecular Biophysics (167)
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Number of items at this level: 167.

2025

Mai, Huanghao (2025) Advancing Structural Analysis with Computational Methods Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4p95-d385. https://resolver.caltech.edu/CaltechTHESIS:07252024-205053475

Schaus, Lucas Jean Nicolas (2025) Studies on Scaling Throughput in Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jqng-x012. https://resolver.caltech.edu/CaltechTHESIS:08022024-005547280

2024

Ivy, Tobin William (2024) Implementing and Modeling Gene Drives for Population Modification and Suppression. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/10pa-x574. https://resolver.caltech.edu/CaltechTHESIS:06042024-163846436

Goronzy, Isabel Nadine (2024) Higher-Order Chromatin States and Nuclear Structures Regulating Gene Expression. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8gm2-jn84. https://resolver.caltech.edu/CaltechTHESIS:07272023-175309910

Orta, Anna Karen (2024) Leveraging the ΦX174 Protein Antibiotic to Study MraY Structure, Function, and Regulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ggr0-0n72. https://resolver.caltech.edu/CaltechTHESIS:06042024-022255958

Saladi, Shyam Madhukar (2024) Some Computer Studies of Membrane Proteins, Molecular Chaperones, and Color. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/40cw-kn70. https://resolver.caltech.edu/CaltechTHESIS:10232023-184021847

Stevens, Taylor Anthony (2024) Characterization of a Novel Membrane Protein Insertase in the Mitochondrial Outer Membrane. Dissertation (Ph.D.), California Institute of Technology. https://resolver.caltech.edu/CaltechTHESIS:12092023-142606831

2023

Almhjell, Patrick James (2023) Noncanonical Amino Acid Synthesis by Evolved Tryptophan Synthases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/rcvq-dg51. https://resolver.caltech.edu/CaltechTHESIS:10172022-224813021

Dutka, Przemysław (2023) Cryo-ET Reveals Molecular Details of Multi-Megadalton Bacterial Protein Complexes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/87jm-7v06. https://resolver.caltech.edu/CaltechTHESIS:05092023-163511031

Kuintzle, Rachael Christine (2023) Diversity in Notch Ligand-Receptor Signaling Interactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/w8gj-jb92. https://resolver.caltech.edu/CaltechTHESIS:05302023-215054202

Meyerowitz, Joseph Toshiro (2023) Engineering and Rapid Prototyping for Biology in Extreme Conditions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9gbb-n831. https://resolver.caltech.edu/CaltechTHESIS:12022022-073109279

Ousey, James Anthony (2023) Gut Microbiota Modulation of Host Feeding Behavior. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8ghx-2b24. https://resolver.caltech.edu/CaltechTHESIS:11112022-203906821

Pinton Tomaleri, Giovani (2023) Structure and Mechanism of the Human ER Membrane Protein Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/e85y-re86. https://resolver.caltech.edu/CaltechTHESIS:06012023-220838845

Sarai, Nicholas Singh (2023) Engineering Cytochrome P450BM3 for Oxidation and Silicon–Carbon Bond Cleavage of Volatile Methylsiloxanes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/gn1j-fz77. https://resolver.caltech.edu/CaltechTHESIS:05152023-034200704

2022

Banks, Rachel A. (2022) Experimental and Theoretical Studies of Non-Equilibrium Systems: Motor-Microtubule Assemblies and the Human-Earth System. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5ee6-j454. https://resolver.caltech.edu/CaltechTHESIS:11282021-042001335

Esswein, Shannon Rose (2022) Structural Basis of Antibody Recognition of Viruses. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/krjp-se81. https://resolver.caltech.edu/CaltechTHESIS:05202022-005152490

Fry, Michelle Yen (2022) Mechanistic Studies of Tail-Anchored Membrane Protein Targeting to the ER. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/b3yj-c572. https://resolver.caltech.edu/CaltechTHESIS:08232021-203647268

Galstyan, Vahe (2022) Studies in Physical Biology: Exploring Allosteric Regulation, Enzymatic Error Correction, and Cytoskeletal Self-Organization Using Theory and Modeling. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1fzr-1240. https://resolver.caltech.edu/CaltechTHESIS:08242021-212959886

Jette, Claudia Angela (2022) Targeting Fusion Proteins of HIV-1 and SARS-CoV-2. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/pxa2-dy41. https://resolver.caltech.edu/CaltechThesis:04282022-192922044

Petrovic, Stefan (2022) Structure and Function of the Human Nuclear Pore Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/g77e-h329. https://resolver.caltech.edu/CaltechTHESIS:05262022-064823923

Razo-Mejia, Manuel (2022) Physical Biology of Cellular Information Processing. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/kpc2-b345. https://resolver.caltech.edu/CaltechTHESIS:08242021-212609828

Yang, Zhi (2022) Conformational Plasticity of HIV-1 Env and Implications for Vaccine Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/99hp-y284. https://resolver.caltech.edu/CaltechTHESIS:01222022-001845303

Zimmer, Matthew Holden (2022) Cotranslational Pulling Forces Alter Outcomes of Protein Synthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p7vk-cf03. https://resolver.caltech.edu/CaltechTHESIS:07232021-171251780

2021

Cohen, Alexander Armand (2021) Developing Multivalent Nanoparticle Vaccines Against Current and Future Viruses. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/r33z-kj46. https://resolver.caltech.edu/CaltechTHESIS:06082021-015935441

Threatt, Stephanie Denise (2021) In Vivo Activity of Rhodium Metalloinsertors and Exploration of Drug Delivery Systems. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/dmqv-ed54. https://resolver.caltech.edu/CaltechTHESIS:09082020-225341960

Wang, Jingzhou (2021) CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p0kj-9d56. https://resolver.caltech.edu/CaltechTHESIS:05282021-080632319

Zhou, Wen (2021) Single-Cell Analysis of Normal and Perturbed Early T-Cell Developmental Processes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/733t-mg82. https://resolver.caltech.edu/CaltechTHESIS:01292021-130102777

2020

Brugman, Katherine Irene (2020) Pezo-1 Function in Caenorhabditis elegans. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fz4z-c850. https://resolver.caltech.edu/CaltechTHESIS:05312020-153151158

Chure, Griffin Daniel (2020) The Molecular Biophysics of Evolutionary and Physiological Adaptation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/q8h6-xr92. https://resolver.caltech.edu/CaltechTHESIS:06022020-102020436

Fan, Chengcheng (2020) Structure, Function, and Application of Bacterial ABC Transporters. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5t65-0047. https://resolver.caltech.edu/CaltechTHESIS:06012020-160106726

Jung, Yonil (2020) Neurons that Control Social States in Drosophila melanogaster. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/pard-ed88. https://resolver.caltech.edu/CaltechTHESIS:03122020-231054692

Lee, Kyu Hyun (2020) Visual Computations in the Superior Colliculus. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/zn2j-m319. https://resolver.caltech.edu/CaltechTHESIS:06012020-165101402

Wang, Shuai (2020) Co-Translational Protein Targeting and Insertion by SecA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YAQY-3460. https://resolver.caltech.edu/CaltechTHESIS:10022019-105854314

2019

Angeles-Albores, David (2019) A Theory of Genetic Analysis Using Transcriptomic Phenotypes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JRNS-NS05. https://resolver.caltech.edu/CaltechTHESIS:10232018-150005837

Blythe, Emily Elizabeth (2019) Characterization of Adaptor Binding and Substrate Processing by VCP/p97. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9K4M-0C48. https://resolver.caltech.edu/CaltechTHESIS:05222019-125958370

Chen, Wen (2019) Proteomics Profiling and Functional Characterization of Caenorhabditis elegans Excreted/Secreted Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WTMK-7M75. https://resolver.caltech.edu/CaltechTHESIS:06072019-035956740

Frick, Christopher Lee (2019) How Single Cells Sense Smad3 Signal. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WNM4-4R58. https://resolver.caltech.edu/CaltechTHESIS:05222019-160829503

Huber, Ferdinand Michael (2019) Molecular Basis for Ribosomal Protein Protection from Cellular Degradation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4S7C-V170. https://resolver.caltech.edu/CaltechTHESIS:05242019-115311540

Piraner, Dan Ilya (2019) Tunable Thermal Bioswitches as a Control Modality for Next Generation Therapeutics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/DH10-6N61. https://resolver.caltech.edu/CaltechTHESIS:05312019-045041264

Wang, Haoqing (2019) Structure and Dynamics of HIV-1 Env Trimer. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/65VD-VM42. https://resolver.caltech.edu/CaltechTHESIS:02272019-142326751

Wenke, Belinda B. (2019) The Many Roles of the Nitrogenase Iron Protein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8RB1-HC30. https://resolver.caltech.edu/CaltechTHESIS:04222019-175445561

Zhou, Andy (2019) Investigations of DNA-Mediated Redox Signaling Between E.coli DNA Repair Pathways. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/G7NF-S349. https://resolver.caltech.edu/CaltechTHESIS:11262018-103442842

2018

Arias, Renee Justine (2018) Examination of Selenium Incorporation and Product Formation in the Nitrogenase FeMo-Cofactor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5WZV-R440. https://resolver.caltech.edu/CaltechTHESIS:05252018-140505343

Jensen, Elizabeth Hwang (2018) Elucidating the Role of O-GlcNAc Glycosylation in Neurobiology and Neurodegeneration. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9JD4TZ9. https://resolver.caltech.edu/CaltechTHESIS:12192017-155744407

Nguyen, Phong Thanh (2018) Structural and Functional Characterization of the Escherichia coli MetNI Methionine Transporter. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/x9ed-9n64. https://resolver.caltech.edu/CaltechTHESIS:04302018-143201092

2017

Lin, Daniel Hanyang (2017) The Architecture of the Nuclear Pore Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98P5XK8. https://resolver.caltech.edu/CaltechTHESIS:06092017-125142341

Vu, Tran Minh Tri (2017) Studies of the N-end Rule Pathway in Bacteria and Mammals. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9668B5J. https://resolver.caltech.edu/CaltechTHESIS:07022016-190718870

Glasser, Nathaniel Robert (2017) Physiological and Biochemical Mechanisms of Phenazine-Mediated Survival in Pseudomonas aeruginosa. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9SN070S. https://resolver.caltech.edu/CaltechTHESIS:05312017-133325449

Guo, Shaobin (2017) Prototyping Diverse Synthetic Biological Circuits in a Cell-Free Transcription-Translation System. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9CR5RDK. https://resolver.caltech.edu/CaltechTHESIS:03082017-163613964

Herrera, Nadia (2017) Structure and Function of the Mycobacterial Mechanosensitive Channel of Large Conductance, MscL. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9JH3J77. https://resolver.caltech.edu/CaltechTHESIS:05162017-130844945

Kamajaya, Aron (2017) Structural Study of Piezo Channel, a Unique Family of Eukaryotic Mechanosensitive Channel. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9JQ0Z00. https://resolver.caltech.edu/CaltechTHESIS:07182016-144756449

Li, Qi Wen (2017) Biophysical Characterization of an ABC L-methionine Transporter. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9125QN9. https://resolver.caltech.edu/CaltechTHESIS:04022017-212739773

Lieblich, Seth Aharon (2017) Non-Canonical Amino Acid Mutagenesis of Position B28 In Insulin with Proline Analogs. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z90Z71BD. https://resolver.caltech.edu/CaltechTHESIS:05112017-233327193

Mock, Jee Young (2017) The Bag6 Complex: Biological Complexity through Modularity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91C1TXQ. https://resolver.caltech.edu/CaltechTHESIS:06052017-184553539

Wong, Betty Ko (2017) Biophysical Studies of Ligand-gated Ion Channels. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9TT4P0Q. https://resolver.caltech.edu/CaltechTHESIS:05302017-225018783

2016

Davenport, Andrew M. (2016) The Molecular Basis of Lysine Acetylation: Addition, Removal, and Recognition. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9BG2KWK. https://resolver.caltech.edu/CaltechTHESIS:09012015-173735253

Husain, Naeem Shahab (2016) Mapping mRNA and Protein Expression with High Signal-to-Background in Diverse Organisms. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DF6P73. https://resolver.caltech.edu/CaltechTHESIS:02252016-123239637

Lubeck, Eric (2016) Towards in situ Single Cell Systems Biology. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9BK1999. https://resolver.caltech.edu/CaltechTHESIS:02262016-115004310

Martinez, Thomas Farid (2016) Investigations of Pyrrole-Imidazole Polyamide Effects on DNA Replication. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9RF5RZ2. https://resolver.caltech.edu/CaltechTHESIS:06292015-212932175

Owens, Gwen Ellen (2016) Biochemical and Biophysical Characterization of Huntingtin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9TM7835. https://resolver.caltech.edu/CaltechTHESIS:11042015-142900908

Rao, Meera (2016) Mechanisms of Regulation and Fidelity in Tail-Anchored Membrane Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9G73BQN. https://resolver.caltech.edu/CaltechTHESIS:05232016-135949451

Shafaat, Oliver Syed (2016) Temporal Control of Ion Channel Activation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98P5XGX. https://resolver.caltech.edu/CaltechTHESIS:05122016-095434020

2015

Gristick, Harry Benjamin (2015) Investigating the Role of the GET3-GET4/GET5 Interaction During Tail-Anchor Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z95718ZD. https://resolver.caltech.edu/CaltechTHESIS:06052015-162319516

Idigo, Chinenye Abiodun (2015) Structural and Biophysical Characterization of Variants of the Mechanosensitive Channel of Large Conductance (MsCL). Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9542KJ3. https://resolver.caltech.edu/CaltechTHESIS:12152014-153232034

Kreamer, Naomi N. (2015) Ferrous Iron Sensing and Responding in Pseudomonas aeruginosa. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DN4324. https://resolver.caltech.edu/CaltechTHESIS:03092015-135659710

Schaefer, Kathryn Nicole (2015) DNA-Mediated Oxidation of Transcription Factor p53. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9BV7DJQ. https://resolver.caltech.edu/CaltechTHESIS:02122015-130640999

2014

Berry, Alexandria Helen T. (2014) Designing Conformational Control of Human Tissue Transglutaminase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WW1E-VT19. https://resolver.caltech.edu/CaltechTHESIS:02282014-131036761

Akopian, David (2014) Phospholipids and a Protein-Conducting Channel Regulate Cotranslational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PMBG-Y424. https://resolver.caltech.edu/CaltechTHESIS:05202014-104709210

Ariosa, Aileen Renia (2014) Mechanisms of Substrate Selection by the Signal Recognition Particle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/AEDK-0925. https://resolver.caltech.edu/CaltechTHESIS:05302014-103528106

Brown, Joshua Micah (2014) Investigation of Receptors for the Modulation of Neuronal Growth by Chondroitin Sulfate. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z90G3H45. https://resolver.caltech.edu/CaltechTHESIS:09162013-140043647

Chitsaz, Mohsen (2014) Protein Structure Refinement Algorithms. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7731-QM74. https://resolver.caltech.edu/CaltechTHESIS:06072014-074257676

Hamdouche, Samy (2014) Engineered Antibody and Monobody Domains with T Cell Receptor-Like Selectivity for Tumor Associated Peptide-MHC Antigens. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9WH2N02. https://resolver.caltech.edu/CaltechTHESIS:06062014-175608943

Lee, Toni Marie (2014) Computationally-Guided Thermostabilization of the Primary Endoglucanase from Hypocrea jerorina for Cellulosic Biofuel Production. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9S180G0. https://resolver.caltech.edu/CaltechTHESIS:11172013-001549340

Lovely, Geoffrey A. (2014) Biophysics of V(D)J Recombination and Genome Packaging: In Singulo Studies on RAG, HMGB1, and TFAM. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9W9573H. https://resolver.caltech.edu/CaltechTHESIS:06072014-140700155

Sosa Padilla Araujo, Bernardo (2014) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9KP805N. https://resolver.caltech.edu/CaltechTHESIS:05052014-122744794

Su, Tsu-Te Judith (2014) Label-free Detection of Single Molecule Using Microtoroid Optical Resonators. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EHWP-DH17. https://resolver.caltech.edu/CaltechTHESIS:05302014-140200007

Tan, Frederick Eng How (2014) Brfl Post-Transcriptionally Regulates Pluripotency and Differentiation Responses Downstream of Erk MAP Kinase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MM53-XC23. https://resolver.caltech.edu/CaltechTHESIS:05292014-234047875

Walkup, Ward Gale IV (2014) Biochemical Studies of Postsynaptic Density Signaling Proteins With a Focus on synGAP and PDZ Domains. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9N877R8. https://resolver.caltech.edu/CaltechTHESIS:12182013-191308687

2013

Bialecka-Fornal, Maja I. (2013) Single-Cell Analysis of the Physiology of Mechanosensation in Bacteria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7SRD-WS94. https://resolver.caltech.edu/CaltechTHESIS:05142013-213725125

Chartron, Justin William (2013) The Structure of a Transmembrane Protein Sorting Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QVCV-8A76. https://resolver.caltech.edu/CaltechTHESIS:10012012-155636249

Moore, Matthew Michaels (2013) Applications of Computational Protein Design to Red Fluorescent Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6876-A570. https://resolver.caltech.edu/CaltechTHESIS:09132012-234333515

Ting, Christina Lei (2013) A Novel Method for Studying Nucleated Pathways in Membranes: Development and Applications for Gene Delivery. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8FTH-8H35. https://resolver.caltech.edu/CaltechTHESIS:08282012-110955629

Venturelli, Ophelia Shalini (2013) Role of Feedback and Dynamics of a Gene Regulatory Network. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WGK3-Y839. https://resolver.caltech.edu/CaltechTHESIS:06072013-095239958

2012

Ngo, John Tuan (2012) Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XNEA-GM53. https://resolver.caltech.edu/CaltechTHESIS:01122012-225941177

Frazier, Shawnalea Jimee (2012) Optimization of the GluC1/IVM Neuronal Silencing Tool via Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4AGK-FP05. https://resolver.caltech.edu/CaltechTHESIS:05252012-121406958

Johnson, Stephanie Lynn (2012) DNA Mechanics and Transcriptional Regulation in the E. coli lac Operon. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/W40T-PD39. https://resolver.caltech.edu/CaltechTHESIS:05112012-140027276

Liu, Cambrian Yangshao (2012) Characterization of an Unusual Collection of Olfactory Neurons in the Nose. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/47P6-2H66. https://resolver.caltech.edu/CaltechTHESIS:05062012-022516031

Materna, Stefan Christian (2012) The Regulatory Origin of Oral and Aboral Mesoderm in Sea Urchin Embryos. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/77VQ-8A52. https://resolver.caltech.edu/CaltechTHESIS:05122012-162210497

Matzen, Kelly Jean (2012) Engineering of Dengue Virus Refractoriness in Aedes aegypti and Development of an Underdominant Gene Drive System in Drosophila melanogaster. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YNFQ-WM56. https://resolver.caltech.edu/CaltechTHESIS:05192012-130917004

Nisthal, Alex (2012) Accelerating the Interplay Between Theory and Experiment in Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9833Q2F. https://resolver.caltech.edu/CaltechTHESIS:02062012-154120957

Romero, Philip Anthony (2012) Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7W9R-Y338. https://resolver.caltech.edu/CaltechTHESIS:03172012-160452929

Zuckerman, Jonathan Eric (2012) Targeting Tumors and the Kidney with siRNA Nanoparticles and Evaluation of Extracellular MicroRNA-based Methodologies to Track Their Activity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/P4FF-NQ42. https://resolver.caltech.edu/CaltechTHESIS:05182012-134600511

2011

Ballor, Nicholas R. (2011) Hydrogenases and Hydrogen Sensors in the Symbiotic Microbial Communities of Wood-Feeding Termites. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/621E-9221. https://resolver.caltech.edu/CaltechTHESIS:08182010-104705359

Barnet, Matthew Edward (2011) Dynamics of Sea Urchin Gastrulation Revealed by Tracking Cells of Diverse Lineage and Regulatory State. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9MJ2-7Q87. https://resolver.caltech.edu/CaltechTHESIS:10152010-141750757

Bugg, Charles Walter (2011) Domain Organization of Mutant Huntingtin Fibrils. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XAYY-9E20. https://resolver.caltech.edu/CaltechTHESIS:09192010-204534950

Ernst, Russell J. (2011) The Biological Activity of Rhodium Metalloinsertors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3K6K-JX55. https://resolver.caltech.edu/CaltechTHESIS:05272011-113632785

Jaru-Ampornpan, Peera (2011) Post-Translational Membrane Protein Targeting by the Chloroplast Signal Recognition Particle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RDKZ-8094. https://resolver.caltech.edu/CaltechTHESIS:05242011-165030719

Kuntz, Steven Gregory (2011) hlh-1 and the C. elegans Body Wall Muscle Transcriptional Differentiation Network. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/18XS-YM65. https://resolver.caltech.edu/CaltechTHESIS:10212010-102536869

Kushiro, Keiichiro (2011) Directing Cellular Traffic Using Geometric and Biomolecular Signal Alterations. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/61Y2-AC28. https://resolver.caltech.edu/CaltechTHESIS:10122010-134624507

Phillips, John Wilson (2011) Biological Activity of a Py-Im Polyamide Androgen Receptor Antagonist. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MPH7-D492. https://resolver.caltech.edu/CaltechTHESIS:06022011-172257819

Tadmor, Arbel David (2011) Phage-Host Interaction in Nature. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/68Q5-D532. https://resolver.caltech.edu/CaltechTHESIS:05252011-233927917

Ward, Catherine Marie (2011) Medea Selfish Genetic Elements as Tools for Altering Traits of Wild Populations: A Theoretical Analysis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/T656-ZN91. https://resolver.caltech.edu/CaltechTHESIS:05312011-123357339

Yang, Jennifer Chuen-Hsien (2011) Following Motion of Early Heart Development at the Cellular Level Using Confocal Microscopy in Transgenic Quail Embryos. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Y0YB-2312. https://resolver.caltech.edu/CaltechTHESIS:08312010-135100976

2010

Bower, Kiowa San (2010) Chemical-Scale Studies of the 5-HT₃ and D2 Dopamine Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/17AK-6J11. https://resolver.caltech.edu/CaltechTHESIS:03142010-163350106

Dalal, Chiraj Kiran (2010) Causes and Consequences of Gene Expression Noise. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MHSR-9875. https://resolver.caltech.edu/CaltechTHESIS:03312010-150904525

Hodas, Jennifer Jin Lee (2010) Elucidating the Hippocampal Dopaminergic Subproteome with Novel Bioorthogonal Techniques. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/DBGH-J143. https://resolver.caltech.edu/CaltechTHESIS:10012009-223603699

Wawrousek, Karen Elizabeth (2010) Contributions of Dna2 and the Tim/Tipin Complex to Genomic Stability. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QYSH-WH15. https://resolver.caltech.edu/CaltechTHESIS:01032010-225423037

2009

Anderson, Megan Jo (2009) Microfluidics-Based Strategies for Protein Crystallography. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/P5ZD-0S21. https://resolver.caltech.edu/CaltechETD:etd-10172008-222221

Bayer, Travis Scott (2009) Synthetic Regulation and Genetic Control of an Ecological Strategy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3GDB-C409. https://resolver.caltech.edu/CaltechETD:etd-10162008-131654

Gama, Cristal Ivette (2009) Understanding the Chemical Basis of Neuronal Development and Communication: I. The Role of Fucose α(1-2) Galactose Carbohydrates in Neuronal Growth. II. Structure-Function Analysis of Chondroitin Sulfate in the Brain. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/CDGH-MJ49. https://resolver.caltech.edu/CaltechETD:etd-10302008-123855

Gordon, Sean Patrick (2009) Hormone and Gene Feedback during Development and Regeneration in Arabidopsis thaliana. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/T3CR-TC54. https://resolver.caltech.edu/CaltechETD:etd-05022009-103703

Keeffe, Jennifer Rae (2009) Engineering Cyanovirin-N for Enhanced Viral Neutralization. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QSJH-5X56. https://resolver.caltech.edu/CaltechETD:etd-12232008-110031

Klein, Joshua Simon (2009) Investigations in the Design and Characterization of HIV-1 Neutralizing Molecules. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QPEC-8Y25. https://resolver.caltech.edu/CaltechETD:etd-06042009-131723

Lin, Alexander Pei-Den Peter (2009) Noninvasive Imaging of Carotid Arterial Strain Using Displacement-Encoded MRI. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Q7NT-XN05. https://resolver.caltech.edu/CaltechETD:etd-06072009-232351

Murrey, Heather Elizabeth (2009) Identification and Characterization of the Plasticity-Relevant Fucose-α(1-2) Galactose Glycoproteome from Mouse Brain. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QG38-9P18. https://resolver.caltech.edu/CaltechETD:etd-12182008-145714

Rice, Adrian Edward (2009) Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2P16-3X70. https://resolver.caltech.edu/CaltechETD:etd-05192009-163326

Tanrikulu, Ismet Çag˘ler (2009) Discovery of Aminoacyl-tRNA Synthetase Mutants for the Incorporation of Non Canonical Amino Acids into Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/E7D5-HN96. https://resolver.caltech.edu/CaltechETD:etd-05232009-204358

2008

Maerkl, Sebastian Josef (2008) Microfluidic Large Scale Integration and its Application to Systems Biology. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5CMX-CV08. https://resolver.caltech.edu/CaltechETD:etd-05222007-141119

Mohanty, Sarina (2008) Akt Phosphorylation of Drosophila Heat-Shock Factor: A Signature for Stress Resistance. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9CV4FQJ. https://resolver.caltech.edu/CaltechETD:etd-05302008-150414

Olson, Clifford Anders (2008) mRNA Display Selection Using a Combinatorial 10FnIII Protein Library for Detection and Modulation of Cellular Processes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9RCG-P320. https://resolver.caltech.edu/CaltechETD:etd-01082008-160438

Otey, Christopher Richard (2008) Structural and Functional Exploration of an Artificial Family of Cytochromes P450. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MZQM-N011. https://resolver.caltech.edu/CaltechETD:etd-06112008-094638

Xiu, Xinan Joanne (2008) Structure-Function Studies of Nicotinic Acetylcholine Receptors Using Unnatural Amino Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HWGS-7Z13. https://resolver.caltech.edu/CaltechETD:etd-12142007-125144

2007

Alvizo, Oscar (2007) Computational Protein Design Force Field Optimization: A Negative Design Approach. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NYVY-7Z76. https://resolver.caltech.edu/CaltechETD:etd-05212007-164114

Ashby, Meredith Howard (2007) The Sea Urchin Regulome in Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/523T-5R49. https://resolver.caltech.edu/CaltechETD:etd-10192006-114144

Austin, Ryan James (2007) Solving Molecular Recognition Problems with Evolvable Peptide Motifs. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/H8BY-M951. https://resolver.caltech.edu/CaltechETD:etd-05072007-135522

Khidekel, Nelly (2007) A Chemoenzymatic Strategy toward Understanding O-GlcNAc Glycosylation in the Brain. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MT8P-JB95. https://resolver.caltech.edu/CaltechETD:etd-03022007-083916

Lassila, Jonathan Kyle (2007) Methods for Computational Enzyme Design and Application to the Chorismate-Prephenate Rearrangement. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4xm1-h147. https://resolver.caltech.edu/CaltechETD:etd-12182006-150535

Millward, Steven Wesley (2007) The Design, Synthesis, and Evolution of Macrocyclic mRNA Display Libraries Containing Unnatural Amino Acids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/THV4-2A51. https://resolver.caltech.edu/CaltechETD:etd-05142007-161158

Murphy, Gavin Erick (2007) Cryoelectron Tomography of Bacteria and their Macromolecular Machines. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/517B-0Z68. https://resolver.caltech.edu/CaltechETD:etd-05212007-162731

Revilla-i-Domingo, Roger (2007) CIS-Regulatory Analysis of the Sea Urchin Delta Gene: Validating the Architecture of the Gene Regulatory Network Model for Early Micromere Lineage Specification. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/G9GQ-H097. https://resolver.caltech.edu/CaltechETD:etd-06042007-145414

2006

Collins, Cynthia Hollie (2006) Directed Evolution of the Transcriptional Activator LuxR. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/61qd-8j79. https://resolver.caltech.edu/CaltechETD:etd-12272005-160649

Cope, Gregory Allan (2006) Regulation of SCF Ubiquitin Ligases by Jab1/Csn5 and the Cop9 Signalosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/43JP-NQ47. https://resolver.caltech.edu/CaltechETD:etd-07222005-141530

Kulkarni, Rajan P. (2006) Mechanics of the Cytoskeleton: Examining the Dynamics of Cytoplasmic Transport through Fluorescence Microscopy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/85ea-ed40. https://resolver.caltech.edu/CaltechETD:etd-03112006-214258

Mao, Jessica (2006) Applications of Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/13A4-Z652. https://resolver.caltech.edu/CaltechETD:etd-02102006-100744

Marcus, Joshua Scott (2006) Single Mammalian Cell Gene Expression Analysis Using Microfluidics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/M3GA-PT31. https://resolver.caltech.edu/CaltechETD:etd-06282006-103230

McGarvey, Raymond Timothy James (2006) Ultra-Sensitive Absorption Measurements through Cavity-Enhanced Spectroscopy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/CGYD-6J27. https://resolver.caltech.edu/CaltechETD:etd-09202008-110124

Meyer, Michelle Margaret (2006) Exploring Protein Sequence Space Using Computationally Directed Recombination. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YJPE-CD11. https://resolver.caltech.edu/CaltechETD:etd-05262006-112358

Zollars, Eric Stafford (2006) Force Field Development in Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/55br-9a21. https://resolver.caltech.edu/CaltechETD:etd-06052006-155305

2005

Borths, Elizabeth Loraine (2005) Structural and Biochemical Characterization of the Vitamin B₁₂ ABC Transporter, BtuCD-F. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/kkkr-tk81. https://resolver.caltech.edu/CaltechETD:etd-01032005-142802

Hom, Geoffrey Kai Tong (2005) Advances in Computational Protein Design: Development of More Efficient Search Algorithms and their Application to the Full-Sequence Design of Larger Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/M4R9-YM51. https://resolver.caltech.edu/CaltechETD:etd-05302005-223153

Mah, Angie Siu Yee (2005) Regulation of Protein Kinase Dbf2 in Mitotic Exit. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NS1Z-3K87. https://resolver.caltech.edu/CaltechETD:etd-05242005-130533

Meinhold, Peter (2005) Engineering Cytochrome P450 BM-3 for Selective Hydroxylation of Alkanes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/aats-ca30. https://resolver.caltech.edu/CaltechETD:etd-06032005-113204

Shah, Premal S. (2005) Advances in Force Field Development and Sequence Optimization Methods for Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/mg9x-s593. https://resolver.caltech.edu/CaltechETD:etd-04042005-142719

Takahashi, Terry Torao (2005) In Vitro Selection of RNA Binding Peptides. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9X0X-PG47. https://resolver.caltech.edu/CaltechETD:etd-05262005-163739

2004

Giannetti, Anthony Michael (2004) Biochemical, Biophysical, and Cellular Investigations of the Interactions of Transferrin Receptor with Transferrin and the Hereditary Hemochromatosis Protein, HFE. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/06QJ-JW93. https://resolver.caltech.edu/CaltechETD:etd-05262004-173612

Gong, Ying (2004) Cell Polarity and Morphogenesis: Functions and Mechanisms of Cell Divisions in Vertebrate Gastrulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5TZ8-W842. https://resolver.caltech.edu/CaltechETD:etd-06052004-132200

Huang, Po-Ssu (2004) Computational Design and Experimental Characterization of Protein Oligomers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3DZW-2R54. https://resolver.caltech.edu/CaltechETD:etd-06012004-214823

Kalani, M. Yashar S. (2004) Structure and Function Studies of the Human Dopamine Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/T6NV-7W30. https://resolver.caltech.edu/CaltechETD:etd-05042004-203854

2003

Datta, Deepshikha (2003) Protein-Ligand Interactions: Docking, Design and Conformation Change. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/36FS-2262. https://resolver.caltech.edu/CaltechETD:etd-03242003-111426

Ewald, Andrew Josef (2003) The Molecular Control of Cell Movements during Early Vertebrate Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/67Z0-H535. https://resolver.caltech.edu/CaltechETD:etd-03312003-125746

Mo, Chunhui (2003) Synaptic Learning Rules for Local Synaptic Interactions: Theory and Application to Direction Selectivity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EAK1-BQ32. https://resolver.caltech.edu/CaltechETD:etd-05222003-170638

Quezada, Cindy María (2003) Histidine Phosphorylation in Bacterial Chemotaxis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8DNJ-GX96. https://resolver.caltech.edu/CaltechETD:etd-05302003-145522

Thorsen, Todd Addison (2003) Microfluidic Technologies for High-Throughput Screening Applications. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QGWY-VX32. https://resolver.caltech.edu/CaltechETD:etd-12012002-092026

Voigt, Christopher Ashby (2003) Computationally Optimizing the Directed Evolution of Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/E4GF-EQ41. https://resolver.caltech.edu/CaltechETD:etd-08192002-161141

2002

Bolon, Daniel N. (2002) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/W7F3-DS14. https://resolver.caltech.edu/CaltechETD:etd-01252002-100801

Chen, Tianxin (Cynthia) (2002) Regulatory Mechanisms of the Heat Shock Response. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4BC0-RM51. https://resolver.caltech.edu/CaltechTHESIS:01252012-152553827

Shuey, David John (2002) A Detailed Analysis of the DNA Binding Properties and the Affinity Purification of the Drosophila Heat-Shock Transcription Factor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/y91j-s092. https://resolver.caltech.edu/CaltechTHESIS:01312012-161653671

Strop, Pavel (2002) Characterization of the Mechanosensitive Channel of Large Conductance. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nkqb-gd95. https://resolver.caltech.edu/CaltechETD:etd-05092002-155216

2001

Herman, David Matthew (2001) Stereochemically Modified Polyamides for Recognition in the Minor Groove of DNA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/vsf2-fe75. https://resolver.caltech.edu/CaltechTHESIS:03122014-104807866

Martin, Warham Lance (2001) Protein-Protein Recognition: The Neonatal Fc Receptor and Immunoglobulin G. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9ek6-6833. https://resolver.caltech.edu/CaltechTHESIS:03072014-143524462

1996

Arn, Eric (1996) The 2'-5' RNA ligase of Escherichia coli : purification, cloning, and investigations of in vivo function. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/d36x-7p54. https://resolver.caltech.edu/CaltechETD:etd-09122006-130201

1995

Halsell, Susan Richardson (1995) Expression and localization of Hsp83 RNA in the early Drosophila embryo. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/cx4q-tz48. https://resolver.caltech.edu/CaltechETD:etd-10092007-075248

Stack, Jeffrey H. (1995) Protein and phosphatidylinositol kinases in yeast protein sorting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ayzy-yn85. https://resolver.caltech.edu/CaltechETD:etd-10262007-081900

1992

Tavtigian, Sean Vahram (1992) The regulatory capacity of the protooncogene c-myc. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/gqf9-4979. https://resolver.caltech.edu/CaltechTHESIS:09142011-101754107

1986

Meyer, Paul Wells (1986) The Avoidance Response of Phycomyces in a Controlled Environment. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/s6zv-r568. https://resolver.caltech.edu/CaltechTHESIS:04162019-154502622

1985

Segall, Jeffrey Edward (1985) Chemotaxis of Escherichia coli Studied Using Ionophoretic Stimulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6r2y-ba72. https://resolver.caltech.edu/CaltechTHESIS:02132019-181420941

1967

Strauss, James Henry (1967) Studies on the RNA of Bacteriophage MS2. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1WZB-AY91. https://resolver.caltech.edu/CaltechETD:etd-10102002-121043

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