Browse by Committee Member

2020

Reichermeier, Kurt Michael (2020) Quantitative Characterization of Composition and Regulation of Cullin-RING Ubiquitin Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0WX7-2Q56. https://resolver.caltech.edu/CaltechTHESIS:12122019-091017133

2019

Blythe, Emily Elizabeth (2019) Characterization of Adaptor Binding and Substrate Processing by VCP/p97. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9K4M-0C48. https://resolver.caltech.edu/CaltechTHESIS:05222019-125958370

Yu, Helen (2019) Subunit Selective Degradation of WIZ, a Lenalidomide- and Pomalidomide-Dependent Substrate of E3 Ubiquitin Ligase CRL4CRBN. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z7PK-NH81. https://resolver.caltech.edu/CaltechTHESIS:04232019-210733826

2018

Donaldson, Gregory Paul (2018) Colonization of the Intestinal Surface by Indigenous Microbiota. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6EZ0-3007. https://resolver.caltech.edu/CaltechTHESIS:05082018-122340793

2017

Henning, Ryan Kenneth (2017) Targeting Undruggable Oncoprotein Epitopes with Protein Catalyzed Capture Agents. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9CJ8BJG. https://resolver.caltech.edu/CaltechTHESIS:06022017-070813473

Li, Hanqing (2017) Development of a High-Throughput Protein Interaction Assay and its Applications. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9Q23X9R. https://resolver.caltech.edu/CaltechTHESIS:05292017-183651116

Liu, Raymond (2017) Mechanisms of Drp1 Recruitment to Mitochondria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z99Z92ZF. https://resolver.caltech.edu/CaltechTHESIS:05312017-190514797

2016

Davenport, Andrew M. (2016) The Molecular Basis of Lysine Acetylation: Addition, Removal, and Recognition. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9BG2KWK. https://resolver.caltech.edu/CaltechTHESIS:09012015-173735253

Wadas, Brandon Christopher (2016) Biochemical and Genetic Studies of the N-End Rule Pathway in Yeast and Mammals. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91V5BZQ. https://resolver.caltech.edu/CaltechTHESIS:06022016-162251299

2015

Ahmed, Alysia Ashley (2015) Structural Characterization of Pro-inflammatory and Anti-inflammatory Immunoglobulin G Fc Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9GT5K33. https://resolver.caltech.edu/CaltechTHESIS:05292015-064617250

Miles, Timothy Francis (2015) Binding Site Structure and Stoichiometry in Serotonin Type 3 Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9T151MC . https://resolver.caltech.edu/CaltechTHESIS:07142014-132743727

Mosadeghi, Ruzbeh (2015) Mechanistic Dissection of the Cop9 Signalosome’s Deneddylation Activity on Cullin-RING Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9P26W3G. https://resolver.caltech.edu/CaltechTHESIS:05312015-231120184

Schaefer, Kathryn Nicole (2015) DNA-Mediated Oxidation of Transcription Factor p53. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9BV7DJQ. https://resolver.caltech.edu/CaltechTHESIS:02122015-130640999

2014

Kym, Eugene Yongshik (Gene) (2014) Engineered Discoidin Domain from Factor VIII Binds αvβ3 Integrin with Antibody-like Affinity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PTZH-PB29. https://resolver.caltech.edu/CaltechTHESIS:05302014-171245991

Nichols, Weston A. (2014) Lynxl and the β2V287L Mutation Affect the Stoichiometry of the α4β2 Nicotinic Acetylcholine Receptor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2S9B-R910. https://resolver.caltech.edu/CaltechTHESIS:05292014-190146869

2013

Kolawa, Natalie J. (2013) Proteomic Analysis of the Cdc48/Ubx Network Identifies a Role for Ubx2 in the Regulation of Lipid Biosynthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/FN9G-KV67. https://resolver.caltech.edu/CaltechTHESIS:05282013-142345187

Schwarzkopf, Ma'ayan (2013) Engineering Nucleic Acid Mechanisms for Regulation and Readout of Gene Expression: Conditional Dicer Substrate Formation and Sensitive Multiplexed Northern Blots. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z94Q7S0V. https://resolver.caltech.edu/CaltechTHESIS:05212013-161536447

Venturelli, Ophelia Shalini (2013) Role of Feedback and Dynamics of a Gene Regulatory Network. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WGK3-Y839. https://resolver.caltech.edu/CaltechTHESIS:06072013-095239958

2012

Ngo, John Tuan (2012) Noncanonical Amino Acids in the Interrogation of Cellular Protein Synthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XNEA-GM53. https://resolver.caltech.edu/CaltechTHESIS:01122012-225941177

Chang, Kuang-Jung (2012) A Role for Protein Kinase Dbf2-Mob1 in Mitotic Exit. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z92F7KFT. https://resolver.caltech.edu/CaltechTHESIS:06112012-092401902

Pierce, Nathan William (2012) Sequential Processivity and CAND1 Regulate SCF Ubiquitin Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ME1H-AK32. https://resolver.caltech.edu/CaltechTHESIS:11282011-135435821

Shen, Yue (2012) Interkingdom Communication of a Bacterial Mutualist and its Mammalian Host. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/56YV-8J33. https://resolver.caltech.edu/CaltechTHESIS:06062012-145546209

2011

Chow, Janet (2011) A Pathobiont of the Mammalian Microbiota Balances Intestinal Inflammation and Colonization. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4FZ1-A113. https://resolver.caltech.edu/CaltechTHESIS:05022011-211415511

Ernst, Russell J. (2011) The Biological Activity of Rhodium Metalloinsertors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3K6K-JX55. https://resolver.caltech.edu/CaltechTHESIS:05272011-113632785

Fortini, Barbara Karmen Kraatz (2011) Biochemical and Genetic Studies of Genomic Stability. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZH26-B677. https://resolver.caltech.edu/CaltechTHESIS:05172011-123048725

Gomez, Tara Adele (2011) Mutational Analysis of Ubiquitin Shuttle Receptor Docking Sites on the 26S Proteasome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/K9K3-0105. https://resolver.caltech.edu/CaltechTHESIS:05232011-170710428

2010

Carvalho, Gil Bastos de (2010) Drosophila Feeding Behavior and Demographic Mechanisms of Lifespan Extension. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NMN1-N566. https://resolver.caltech.edu/CaltechTHESIS:06022010-183440587

Hodas, Jennifer Jin Lee (2010) Elucidating the Hippocampal Dopaminergic Subproteome with Novel Bioorthogonal Techniques. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/DBGH-J143. https://resolver.caltech.edu/CaltechTHESIS:10012009-223603699

Luong, Tinh Nghi (2010) Signaling Proteins in the Post-Synaptic Density. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/GQ1D-CY75. https://resolver.caltech.edu/CaltechTHESIS:06012010-124413933

2009

Gordon, Sean Patrick (2009) Hormone and Gene Feedback during Development and Regeneration in Arabidopsis thaliana. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/T3CR-TC54. https://resolver.caltech.edu/CaltechETD:etd-05022009-103703

Ottesen, Elizabeth Ann (2009) The Biology and Community Structure of CO₂-Reducing Acetogens in the Termite Hindgut. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/V57J-FB39. https://resolver.caltech.edu/CaltechETD:etd-10032008-170935

Seah, Adeline (2009) EGF, WNT & HOX Interactions during Patterning of Caenorhabditis elegans Equivalence Groups. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/N559-AE78. https://resolver.caltech.edu/CaltechETD:etd-05242009-123432

2008

Green, Jennifer Leigh (2008) The C. elegans ROR Receptor Tyrosine Kinase, CAM-1, Regulates Wnt Signaling by Two Distinct Mechanisms. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3KR8-VM32. https://resolver.caltech.edu/CaltechETD:etd-05272008-112700

Zid, Brian Matthew (2008) Translational Control Mediates Lifespan Extension Due to Dietary Restriction in Drosophila. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8DZY-WB19. https://resolver.caltech.edu/CaltechETD:etd-02052008-020618

2007

Detmer, Scott A. (2007) The Role of Mitofusin Proteins in Mitochondrial Fusion and Disease. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7MXP-WS63. https://resolver.caltech.edu/CaltechETD:etd-04132007-181115

Ghaboosi, Nazli (2007) Genetic Inhibition of the Ubiquitin-Proteasome Pathway: Insights Into Proteasomal Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PNPS-JR40. https://resolver.caltech.edu/CaltechETD:etd-05242007-234932

Ueda, Christine Terumi (2007) Targeting Human Telomerase RNA via Biochemical and in vitro Selection Methods. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2NK8-KK06. https://resolver.caltech.edu/CaltechETD:etd-09052006-214421

2006

Bingol, Baris (2006) Ubiquitin-Proteasome System at the Synapse. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/qyq5-k147. https://resolver.caltech.edu/CaltechETD:etd-05272006-184911

Cope, Gregory Allan (2006) Regulation of SCF Ubiquitin Ligases by Jab1/Csn5 and the Cop9 Signalosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/43JP-NQ47. https://resolver.caltech.edu/CaltechETD:etd-07222005-141530

Graumann, Johannes (2006) Implementation of Multidimensional Protein Identification Technology and its Application to the Characterization of Protein Complexes in Bakers Yeast. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/J3V1-QQ44. https://resolver.caltech.edu/CaltechETD:etd-05262006-095948

Griffin, Erik Edmund (2006) Mechanisms of Mitochondrial Fusion and Fission. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/902F-8M09. https://resolver.caltech.edu/CaltechETD:etd-05242006-134647

Lacenere, Christopher J. (2006) Advances in Single Molecule Nucleic Acid Sequencing. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/CA4B-S389. https://resolver.caltech.edu/CaltechETD:etd-09302006-140602

2005

Ambroggio, Xavier Ignacio (2005) Structural and Functional Studies of Jamm Domain Proteins and Their Role in the Ubiquitin System. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EVW4-CC51. https://resolver.caltech.edu/CaltechETD:etd-09302004-090155

Copeland, Jeffrey Michael (2005) Identification of Novel Cell Death Regulators in C. elegans and Drosophila. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7T3M-DY09. https://resolver.caltech.edu/CaltechETD:etd-06012005-114127

Hom, Geoffrey Kai Tong (2005) Advances in Computational Protein Design: Development of More Efficient Search Algorithms and their Application to the Full-Sequence Design of Larger Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/M4R9-YM51. https://resolver.caltech.edu/CaltechETD:etd-05302005-223153

Ja, William Wei-Hua (2005) Peptide Modulators of G Protein Signaling. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WMQ9-8086. https://resolver.caltech.edu/CaltechETD:etd-01032005-161114

Mah, Angie Siu Yee (2005) Regulation of Protein Kinase Dbf2 in Mitotic Exit. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NS1Z-3K87. https://resolver.caltech.edu/CaltechETD:etd-05242005-130533

2004

Azzam, Ramzi Issam (2004) The Role of Net1 Phosphorylation in Regulating CDC14 Release During Mitotic Exit. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/W73K-KK96. https://resolver.caltech.edu/CaltechETD:etd-05142004-140316

Sakamoto, Kathleen Miho (2004) Targeting Proteins for Ubiquitination and Degradation in the Treatment of Human Disease. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2RN6-TE18. https://resolver.caltech.edu/CaltechETD:etd-12292003-134700

2003

Bui, Yêń Kim (2003) Genetic Analysis of LET-23 Mediated IP₃ Signaling in Caenorhabditis elegans. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/92D0-6V64. https://resolver.caltech.edu/CaltechETD:etd-09092002-222935

Kirouac, Martha (2003) cis-Regulatory Control of Three Cell Fate-Specific Genes in Vulval Organogenesis of C. elegans and C. briggsae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3WVY-RM54. https://resolver.caltech.edu/CaltechETD:etd-09252002-111831

2002

Aakalu, Girish Nanda (2002) Building the Molecular Machinery of Memory: Local Protein Synthesis in Hippocampal Neurons. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/CAY9-6643. https://resolver.caltech.edu/CaltechTHESIS:01232012-132700275

Du, Fangyong (2002) Allosteric Activation of the Ubiquitin ligase UBR 1 by Short Peptides: Molecular Mechanisms and Physiological Functions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/S3VT-0641. https://resolver.caltech.edu/CaltechTHESIS:02232012-110128910

Vernooy, Stephanie Yeager (2002) Identification of Apoptotic Regulators in Drosophila and their Nonapoptotic Roles in Spermatogenesis: Implications for the Existence of a "Caspase Cassette" which Regulates Diverse Biological Processes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/zqpk-k618. https://resolver.caltech.edu/CaltechTHESIS:02012012-113408899

2001

Brown, Keith B. (2001) Comparative Studies of Vulva Development in C. briggsae. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/n37e-5g80. https://resolver.caltech.edu/CaltechTHESIS:03062014-111730488

Chi, Yong (2001) Negative Regulation of Transcription Factors by Srb10 Cyclin-Dependent Kinase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/tb1q-fz89. https://resolver.caltech.edu/CaltechTHESIS:03072014-113238525

Liu, Yang (2001) Molecular Mechanism of Sulfated Carbohydrate Recognition: Structural and Biochemical Studies of the Cysteine-Rich Domain of Mannose Receptor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fj0v-hx76. https://resolver.caltech.edu/CaltechTHESIS:03102014-140846235

Lyapina, Svetlana Anatol'Evna (2001) Characterization of the Human SCF Ubiquitin Ligases - Structure, Function, and Regulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/apdy-3d30. https://resolver.caltech.edu/CaltechTHESIS:03072014-090536401

Shou, Wenying (2001) Diverse Mechanisms of Regulating the Mitotic Cell Cycle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/TP2C-Q082. https://resolver.caltech.edu/CaltechETD:etd-02032005-110205

2000

Chen, Wen J. (2000) Extragenic Suppressors of Heat Shock Activated GOα. Topic I: Cyclin in Heat Shock Response. Topic II: Signaling by Go and Gq in C. elegans. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2sv5-sd03. https://resolver.caltech.edu/CaltechTHESIS:08112020-100312577

Turner, Glenn Cameron (2000) Functions of the ubiquitin-proteasome system in Saccharomyces cerevisiae : cotranslational protein degradation and regulation of the UBR1 pathway. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/X5T1-TS17. https://resolver.caltech.edu/CaltechETD:etd-09222005-131809

Wang, Minqin (2000) Pattern formation during Caenorhabditis Elegans vulval development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/j9v8-2z18. https://resolver.caltech.edu/CaltechTHESIS:10082013-155308536