Browse by Committee Member

2024

Stevens, Taylor Anthony (2024) Characterization of a Novel Membrane Protein Insertase in the Mitochondrial Outer Membrane. Dissertation (Ph.D.), California Institute of Technology. https://resolver.caltech.edu/CaltechTHESIS:12092023-142606831

2023

Dam, Kim-Marie Anh (2023) Structural Insights into the Conformational Plasticity and Antibody Recognition of HIV-1 Env. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8pvb-dx31. https://resolver.caltech.edu/CaltechTHESIS:06022023-003659646

Pinton Tomaleri, Giovani (2023) Structure and Mechanism of the Human ER Membrane Protein Complex. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/e85y-re86. https://resolver.caltech.edu/CaltechTHESIS:06012023-220838845

Tan, Fayth Hui (2023) Animal Regeneration and its Loss: the Mouse as a Model of Limited Regeneration. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/wedb-2f55. https://resolver.caltech.edu/CaltechTHESIS:05292023-182121722

2022

Abdel-Haq, Reem (2022) Gut Microbiome Modulates Microglia Physiology in Homeostatic and Disease States. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ht1j-2461. https://resolver.caltech.edu/CaltechTHESIS:03162022-173632582

Ding, Ke (2022) Imaging Neuropeptide Release and Localization with Genetically Engineered Reporters. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3ey5-9p35. https://resolver.caltech.edu/CaltechTHESIS:06012022-062105760

Su, Christina Janet (2022) Principles of Addressing Specificity in Promiscuous Ligand-Receptor Systems. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/z7dv-m192. https://resolver.caltech.edu/CaltechTHESIS:06022022-032024376

Yang, Zhi (2022) Conformational Plasticity of HIV-1 Env and Implications for Vaccine Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/99hp-y284. https://resolver.caltech.edu/CaltechTHESIS:01222022-001845303

2021

Huang, Xiawei (2021) Molecular Function and Regulation of Aub Arginine Methylation in the piRNA Pathway. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5734-db78. https://resolver.caltech.edu/CaltechTHESIS:05192021-055633048

Varuzhanyan, Grigor (2021) Mitochondrial Dynamics and Mitophagy during Male Germline Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1mes-yw82. https://resolver.caltech.edu/CaltechTHESIS:09232020-201548312

Wang, Ruohan (2021) Identification of New OPA1 Cleavage Site Reveals that Short Isoforms Regulate Mitochondrial Fusion. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8nk6-1502. https://resolver.caltech.edu/CaltechTHESIS:11182020-224422123

2020

Fan, Chengcheng (2020) Structure, Function, and Application of Bacterial ABC Transporters. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5t65-0047. https://resolver.caltech.edu/CaltechTHESIS:06012020-160106726

Reichermeier, Kurt Michael (2020) Quantitative Characterization of Composition and Regulation of Cullin-RING Ubiquitin Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0WX7-2Q56. https://resolver.caltech.edu/CaltechTHESIS:12122019-091017133

Thompson, John Warren Lenzi (2020) Chemical Tools for Studying O-GlcNAc Glycosylation at the Systems Level. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/gx3z-k069. https://resolver.caltech.edu/CaltechTHESIS:06112020-001257003

Wang, Shuai (2020) Co-Translational Protein Targeting and Insertion by SecA. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YAQY-3460. https://resolver.caltech.edu/CaltechTHESIS:10022019-105854314

2019

Basta, David Wagdi (2019) Genetic Determinants of Growth Arrest Survival in the Bacterial Pathogen Pseudomonas aeruginosa and the Role of Proteases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/K6X1-GS91. https://resolver.caltech.edu/CaltechTHESIS:05282019-090132145

Blythe, Emily Elizabeth (2019) Characterization of Adaptor Binding and Substrate Processing by VCP/p97. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9K4M-0C48. https://resolver.caltech.edu/CaltechTHESIS:05222019-125958370

Jafari, Matiar (2019) Neural Correlates of Sensorimotor Control in Human Cortex: State Estimates and Reference Frames. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/TQ35-KH33. https://resolver.caltech.edu/CaltechTHESIS:05302019-163325527

Yi, Lynn Donglin (2019) Statistical Methods for Gene Differential Expression Analysis of RNA-Sequencing. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0YE6-2217. https://resolver.caltech.edu/CaltechTHESIS:10102018-143313907

2017

Vu, Tran Minh Tri (2017) Studies of the N-end Rule Pathway in Bacteria and Mammals. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9668B5J. https://resolver.caltech.edu/CaltechTHESIS:07022016-190718870

Kamajaya, Aron (2017) Structural Study of Piezo Channel, a Unique Family of Eukaryotic Mechanosensitive Channel. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9JQ0Z00. https://resolver.caltech.edu/CaltechTHESIS:07182016-144756449

Li, Qi Wen (2017) Biophysical Characterization of an ABC L-methionine Transporter. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9125QN9. https://resolver.caltech.edu/CaltechTHESIS:04022017-212739773

Liu, Raymond (2017) Mechanisms of Drp1 Recruitment to Mitochondria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z99Z92ZF. https://resolver.caltech.edu/CaltechTHESIS:05312017-190514797

Mock, Jee Young (2017) The Bag6 Complex: Biological Complexity through Modularity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91C1TXQ. https://resolver.caltech.edu/CaltechTHESIS:06052017-184553539

2016

Rao, Meera (2016) Mechanisms of Regulation and Fidelity in Tail-Anchored Membrane Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9G73BQN. https://resolver.caltech.edu/CaltechTHESIS:05232016-135949451

Rojansky, Rebecca Bloom (2016) A Core Mitophagic Machinery Promotes Selective Degradation of Paternal Mitochondria in Mouse Embryos and MEF Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z96Q1V75. https://resolver.caltech.edu/CaltechTHESIS:04292016-193643737

2015

Ghosh, Srimoyee (2015) Establishing the C. elegans Uterine Seam Cell (utse) as a Novel Model for Studying Cell Behavior. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z92F7KCX. https://resolver.caltech.edu/CaltechTHESIS:05202015-102200658

Gristick, Harry Benjamin (2015) Investigating the Role of the GET3-GET4/GET5 Interaction During Tail-Anchor Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z95718ZD. https://resolver.caltech.edu/CaltechTHESIS:06052015-162319516

Idigo, Chinenye Abiodun (2015) Structural and Biophysical Characterization of Variants of the Mechanosensitive Channel of Large Conductance (MsCL). Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9542KJ3. https://resolver.caltech.edu/CaltechTHESIS:12152014-153232034

Mosadeghi, Ruzbeh (2015) Mechanistic Dissection of the Cop9 Signalosome’s Deneddylation Activity on Cullin-RING Ligases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9P26W3G. https://resolver.caltech.edu/CaltechTHESIS:05312015-231120184

Parker, Rell Lin (2015) Lynx1 Modulation of Nicotinic Acetylcholine Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9HM56DT. https://resolver.caltech.edu/CaltechTHESIS:06292014-232713483

Trisnadi, Nathanie Alna (2015) Regulation of Gastrulation Through Dynamic Patterning in the Drosophila Embryo. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9CJ8BGK. https://resolver.caltech.edu/CaltechTHESIS:09082014-171122678

Wang, Andrew Chih-Kae (2015) Investigating the Role of O-GlcNAc Glycosylation in Neurodegeneration. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z97W695K. https://resolver.caltech.edu/CaltechTHESIS:06032015-135024245

Wu, Yunji (2015) Structural Characterizations of the Dimeric Anti-HIV Antibody 2G12 and the HIV-2 Envelope Glycoprotein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98050K6. https://resolver.caltech.edu/CaltechTHESIS:05212015-194407438

2014

Wang, Yun Elisabeth (2014) Characterizing the Regulation of Mitochondrial Nucleoids. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1MN9-DR40. https://resolver.caltech.edu/CaltechTHESIS:05282014-004119763

Akopian, David (2014) Phospholipids and a Protein-Conducting Channel Regulate Cotranslational Protein Targeting. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PMBG-Y424. https://resolver.caltech.edu/CaltechTHESIS:05202014-104709210

Brown, Joshua Micah (2014) Investigation of Receptors for the Modulation of Neuronal Growth by Chondroitin Sulfate. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z90G3H45. https://resolver.caltech.edu/CaltechTHESIS:09162013-140043647

Kym, Eugene Yongshik (Gene) (2014) Engineered Discoidin Domain from Factor VIII Binds αvβ3 Integrin with Antibody-like Affinity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PTZH-PB29. https://resolver.caltech.edu/CaltechTHESIS:05302014-171245991

Loson, Oliver Calvin (2014) Regulation of Mitochondrial Division by the Drp1 Receptors. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/J23G-KQ18. https://resolver.caltech.edu/CaltechTHESIS:05072014-160207088

Rome, Michael Evan (2014) The Get3 ATPase Drives Unidirectional Targeting of Tail-Anchored Membrane Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DZ068N. https://resolver.caltech.edu/CaltechTHESIS:04162014-173759568

2013

Kolawa, Natalie J. (2013) Proteomic Analysis of the Cdc48/Ubx Network Identifies a Role for Ubx2 in the Regulation of Lipid Biosynthesis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/FN9G-KV67. https://resolver.caltech.edu/CaltechTHESIS:05282013-142345187

Nguyen, Thang Xuan (2013) A Study of Protein Targeting Reveals Insights into Mitigating Protein Aggregation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/JA4R-TE24. https://resolver.caltech.edu/CaltechTHESIS:06052013-151748060

Pham, Anh Hoang (2013) Tools for Assessing Mitochondrial Dynamics in Mouse Tissues and Neurodegenerative Models. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/E61Z-9C26. https://resolver.caltech.edu/CaltechTHESIS:09012012-181931478

2012

Dobro, Megan J. (2012) The Structural Biology of HIV Budding and Maturation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/X6XW-5303. https://resolver.caltech.edu/CaltechTHESIS:06012012-133153407

Shen, Yue (2012) Interkingdom Communication of a Bacterial Mutualist and its Mammalian Host. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/56YV-8J33. https://resolver.caltech.edu/CaltechTHESIS:06062012-145546209

2011

Gomez, Tara Adele (2011) Mutational Analysis of Ubiquitin Shuttle Receptor Docking Sites on the 26S Proteasome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/K9K3-0105. https://resolver.caltech.edu/CaltechTHESIS:05232011-170710428

Jaru-Ampornpan, Peera (2011) Post-Translational Membrane Protein Targeting by the Chloroplast Signal Recognition Particle. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RDKZ-8094. https://resolver.caltech.edu/CaltechTHESIS:05242011-165030719

2010

Gold, Daniel A. (2010) Molecular Characterization of the Dbf4/Drf1-Dependent Kinase (DDK) and the DNA Replication Checkpoint Mediator Claspin in Xenopus Egg Extracts. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XG90-5475. https://resolver.caltech.edu/CaltechTHESIS:10232009-160656505

2009

Keeffe, Jennifer Rae (2009) Engineering Cyanovirin-N for Enhanced Viral Neutralization. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QSJH-5X56. https://resolver.caltech.edu/CaltechETD:etd-12232008-110031

Murrey, Heather Elizabeth (2009) Identification and Characterization of the Plasticity-Relevant Fucose-α(1-2) Galactose Glycoproteome from Mouse Brain. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QG38-9P18. https://resolver.caltech.edu/CaltechETD:etd-12182008-145714

Rice, Adrian Edward (2009) Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2P16-3X70. https://resolver.caltech.edu/CaltechETD:etd-05192009-163326

2008

Olson, Clifford Anders (2008) mRNA Display Selection Using a Combinatorial 10FnIII Protein Library for Detection and Modulation of Cellular Processes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9RCG-P320. https://resolver.caltech.edu/CaltechETD:etd-01082008-160438

Poon, Yan Shuen (2008) The Characterization and Structure of Mechanosensitive Channels of Small Conductance. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EBZ2-5D39. https://resolver.caltech.edu/CaltechETD:etd-05292008-144531

2007

Detmer, Scott A. (2007) The Role of Mitofusin Proteins in Mitochondrial Fusion and Disease. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7MXP-WS63. https://resolver.caltech.edu/CaltechETD:etd-04132007-181115

Lu, Carole Chih-Chen (2007) Cranial Neural Crest Cell Migration in the Avian Embryo and the Roles of Eph-A4 and Ephrin-A5. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/v109-k937. https://resolver.caltech.edu/CaltechETD:etd-10132006-153232

2006

Choi, Eun Jung (2006) Development and Applications of Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZNED-BV38. https://resolver.caltech.edu/CaltechETD:etd-06012006-103350

Cope, Gregory Allan (2006) Regulation of SCF Ubiquitin Ligases by Jab1/Csn5 and the Cop9 Signalosome. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/43JP-NQ47. https://resolver.caltech.edu/CaltechETD:etd-07222005-141530

Griffin, Erik Edmund (2006) Mechanisms of Mitochondrial Fusion and Fission. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/902F-8M09. https://resolver.caltech.edu/CaltechETD:etd-05242006-134647

2005

Ambroggio, Xavier Ignacio (2005) Structural and Functional Studies of Jamm Domain Proteins and Their Role in the Ubiquitin System. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EVW4-CC51. https://resolver.caltech.edu/CaltechETD:etd-09302004-090155

Borths, Elizabeth Loraine (2005) Structural and Biochemical Characterization of the Vitamin B₁₂ ABC Transporter, BtuCD-F. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/kkkr-tk81. https://resolver.caltech.edu/CaltechETD:etd-01032005-142802

Leung, Thomas Hin-Chai (2005) Specificity of Transcription Activation by NF-kB Subunits. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/100y-3c61. https://resolver.caltech.edu/CaltechETD:etd-10042004-090452

Mah, Angie Siu Yee (2005) Regulation of Protein Kinase Dbf2 in Mitotic Exit. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NS1Z-3K87. https://resolver.caltech.edu/CaltechETD:etd-05242005-130533

2004

Giannetti, Anthony Michael (2004) Biochemical, Biophysical, and Cellular Investigations of the Interactions of Transferrin Receptor with Transferrin and the Hereditary Hemochromatosis Protein, HFE. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/06QJ-JW93. https://resolver.caltech.edu/CaltechETD:etd-05262004-173612

2002

Tang, Yi (2002) Protein Engineering Using Unnatural Amino Acids: Incorporation of Leucine Analogs into Recombinant Protein in vivo. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4cvy-8295. https://resolver.caltech.edu/CaltechETD:etd-08152006-084149

2001

Chang, Chieh (2001) Signal Transduction, Regulation, and Developmental Logic of EGFR Signaling in C. elegans. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9qcj-az06. https://resolver.caltech.edu/CaltechTHESIS:03112014-080307279

1991

Bowers, Clifford Russell (1991) Parahydrogen and Synthesis Allow Dramatically Enhanced Nuclear Alignment. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/R5TV-Z220. https://resolver.caltech.edu/CaltechETD:etd-04172006-141634