Browse by Advisor

2025

Schaus, Lucas Jean Nicolas (2025) Studies on Scaling Throughput in Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jqng-x012. https://resolver.caltech.edu/CaltechTHESIS:08022024-005547280

2023

Huang, Shan (2023) DNA-Guided Genome Manipulation in Escherichia coli. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3yab-jg50. https://resolver.caltech.edu/CaltechTHESIS:08072022-205043055

2022

Aceves, Aiden Joseph (2022) Machine Learning and Modeling Methods for Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5j34-0d55. https://resolver.caltech.edu/CaltechTHESIS:09092021-024951318

2021

Wang, Jingzhou (2021) CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p0kj-9d56. https://resolver.caltech.edu/CaltechTHESIS:05282021-080632319

2017

Lieblich, Seth Aharon (2017) Non-Canonical Amino Acid Mutagenesis of Position B28 In Insulin with Proline Analogs. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z90Z71BD. https://resolver.caltech.edu/CaltechTHESIS:05112017-233327193

2016

Cahn, Jackson Kenai Blender (2016) Engineering, Predicting, and Understanding Nicotinamide Cofactor Specificity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9QV3JJ8. https://resolver.caltech.edu/CaltechTHESIS:01212016-225223309

2015

Cornejo de los Santos, Emmanuel Lorenzo (2015) Expanding the Toolkit for Synthetic Biology: Frameworks for Native-like Non-natural Gene Circuits. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9M61H64. https://resolver.caltech.edu/CaltechTHESIS:05182015-163708506

Wannier, Timothy Milton (2015) Computationally Guided Monomerization of Red Fluorescent Proteins of the Class Anthozoa. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9571908. https://resolver.caltech.edu/CaltechTHESIS:01272015-110638252

2014

Berry, Alexandria Helen T. (2014) Designing Conformational Control of Human Tissue Transglutaminase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WW1E-VT19. https://resolver.caltech.edu/CaltechTHESIS:02282014-131036761

Chitsaz, Mohsen (2014) Protein Structure Refinement Algorithms. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7731-QM74. https://resolver.caltech.edu/CaltechTHESIS:06072014-074257676

Hamdouche, Samy (2014) Engineered Antibody and Monobody Domains with T Cell Receptor-Like Selectivity for Tumor Associated Peptide-MHC Antigens. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9WH2N02. https://resolver.caltech.edu/CaltechTHESIS:06062014-175608943

Kym, Eugene Yongshik (Gene) (2014) Engineered Discoidin Domain from Factor VIII Binds αvβ3 Integrin with Antibody-like Affinity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/PTZH-PB29. https://resolver.caltech.edu/CaltechTHESIS:05302014-171245991

Lee, Toni Marie (2014) Computationally-Guided Thermostabilization of the Primary Endoglucanase from Hypocrea jerorina for Cellulosic Biofuel Production. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9S180G0. https://resolver.caltech.edu/CaltechTHESIS:11172013-001549340

Mou, Yun (2014) Computational Design of Self-Assembling Proteins and Protein-DNA Nanowires. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9PG1PPV. https://resolver.caltech.edu/CaltechTHESIS:05232014-201621983

Sosa Padilla Araujo, Bernardo (2014) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9KP805N. https://resolver.caltech.edu/CaltechTHESIS:05052014-122744794

2013

Moore, Matthew Michaels (2013) Applications of Computational Protein Design to Red Fluorescent Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6876-A570. https://resolver.caltech.edu/CaltechTHESIS:09132012-234333515

2012

Nisthal, Alex (2012) Accelerating the Interplay Between Theory and Experiment in Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9833Q2F. https://resolver.caltech.edu/CaltechTHESIS:02062012-154120957

2009

Allen, Benjamin Daniel (2009) Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/SNJJ-0Q88. https://resolver.caltech.edu/CaltechETD:etd-05012009-112749

Keeffe, Jennifer Rae (2009) Engineering Cyanovirin-N for Enhanced Viral Neutralization. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QSJH-5X56. https://resolver.caltech.edu/CaltechETD:etd-12232008-110031

Privett, Heidi Kathleen (2009) An Iterative Approach to de novo Computational Enzyme Design and the Successful Application to the Kemp Elimination. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1402-XZ32. https://resolver.caltech.edu/CaltechETD:etd-05272009-091024

2008

Vizcarra, Christina Luisa (2008) Development and Evaluation of Protein Design Methods for Functional Targets. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/G16E-JZ97. https://resolver.caltech.edu/CaltechETD:etd-05292008-140215

2007

Alvizo, Oscar (2007) Computational Protein Design Force Field Optimization: A Negative Design Approach. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NYVY-7Z76. https://resolver.caltech.edu/CaltechETD:etd-05212007-164114

Lassila, Jonathan Kyle (2007) Methods for Computational Enzyme Design and Application to the Chorismate-Prephenate Rearrangement. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4xm1-h147. https://resolver.caltech.edu/CaltechETD:etd-12182006-150535

2006

Choi, Eun Jung (2006) Development and Applications of Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZNED-BV38. https://resolver.caltech.edu/CaltechETD:etd-06012006-103350

Mao, Jessica (2006) Applications of Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/13A4-Z652. https://resolver.caltech.edu/CaltechETD:etd-02102006-100744

Zollars, Eric Stafford (2006) Force Field Development in Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/55br-9a21. https://resolver.caltech.edu/CaltechETD:etd-06052006-155305

2005

Hom, Geoffrey Kai Tong (2005) Advances in Computational Protein Design: Development of More Efficient Search Algorithms and their Application to the Full-Sequence Design of Larger Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/M4R9-YM51. https://resolver.caltech.edu/CaltechETD:etd-05302005-223153

Sarisky, Catherine Ann (2005) Exploration of the Determinants of Protein Structure and Stability by Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/RBSA-R089. https://resolver.caltech.edu/CaltechETD:etd-05272005-121337

Shah, Premal S. (2005) Advances in Force Field Development and Sequence Optimization Methods for Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/mg9x-s593. https://resolver.caltech.edu/CaltechETD:etd-04042005-142719

2004

Huang, Po-Ssu (2004) Computational Design and Experimental Characterization of Protein Oligomers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3DZW-2R54. https://resolver.caltech.edu/CaltechETD:etd-06012004-214823

2003

Datta, Deepshikha (2003) Protein-Ligand Interactions: Docking, Design and Conformation Change. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/36FS-2262. https://resolver.caltech.edu/CaltechETD:etd-03242003-111426

Voigt, Christopher Ashby (2003) Computationally Optimizing the Directed Evolution of Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/E4GF-EQ41. https://resolver.caltech.edu/CaltechETD:etd-08192002-161141

2002

Bolon, Daniel N. (2002) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/W7F3-DS14. https://resolver.caltech.edu/CaltechETD:etd-01252002-100801

Marshall, Shannon Alicia (2002) Stability and Conformational Specificity in Protein Design: Models for Binary Patterning and Electrostatics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4BVY-VN75. https://resolver.caltech.edu/CaltechTHESIS:04302012-143643233

Strop, Pavel (2002) Characterization of the Mechanosensitive Channel of Large Conductance. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nkqb-gd95. https://resolver.caltech.edu/CaltechETD:etd-05092002-155216

2000

Morgan, Chantal Smith (2000) Full Sequence Design of an Alpha-Helical Protein and Investigation of the Importance of Helix Dipole and Capping Effects in Helical Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8wn3-cv27. https://resolver.caltech.edu/CaltechTHESIS:04092019-114920250

1998

Dahiyat, Bassil I. (1998) Protein design automation : principles and practice. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/08j5-w532. https://resolver.caltech.edu/CaltechETD:etd-05132009-113001

Su, Alyce (1998) Backbone flexibility in protein design theory and experiment. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/MY6J-1191. https://resolver.caltech.edu/CaltechTHESIS:05162011-132252955