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Computational Microscopy: Breaking the Limit of Conventional Optics


Ou, Xiaoze (2016) Computational Microscopy: Breaking the Limit of Conventional Optics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9M32SRZ.


Computational imaging is flourishing thanks to the recent advancement in array photodetectors and image processing algorithms. This thesis presents Fourier ptychography, which is a computational imaging technique implemented in microscopy to break the limit of conventional optics. With the implementation of Fourier ptychography, the resolution of the imaging system can surpass the diffraction limit of the objective lens's numerical aperture; the quantitative phase information of a sample can be reconstructed from intensity-only measurements; and the aberration of a microscope system can be characterized and computationally corrected. This computational microscopy technique enhances the performance of conventional optical systems and expands the scope of their applications.

Item Type:Thesis (Dissertation (Ph.D.))
Subject Keywords:Computational Microscopy, Phase retrieval, Image Processing
Degree Grantor:California Institute of Technology
Division:Engineering and Applied Science
Major Option:Electrical Engineering
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Yang, Changhuei
Thesis Committee:
  • Yang, Changhuei (chair)
  • Tai, Yu-Chong
  • Vaidyanathan, P. P.
  • Shapiro, Mikhail G.
  • Cai, Long
Defense Date:5 April 2016
Record Number:CaltechTHESIS:04282016-051723211
Persistent URL:
Related URLs:
URLURL TypeDescription adapted for ch. 3 adapted for ch. 3 adapted for ch. 3 adapted for ch. 2 and ch. 4 adapted for ch. 2 and ch. 5
Ou, Xiaoze0000-0001-9918-0221
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:9688
Deposited By: Xiaoze Ou
Deposited On:10 May 2016 19:43
Last Modified:18 May 2017 19:20

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