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Studies and Applications of Hyperpolarized ¹²⁹-Xe


Shao, Wenjin (2004) Studies and Applications of Hyperpolarized ¹²⁹-Xe. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/M1E8-1F04.


In this thesis, research work concerning studies and applications of hyperpolarized 129-Xe is presented. The research includes two projects. The first project is the measurement and interpretation of the spin-exchange rates between ¹²⁹-Xe and three alkali metals Rb, Cs, and K, for the cell density range of 0.2-0.7 amagats, with the alkali number densities directly measured by the Faraday rotation method. The determination of the constants governing the spin-exchange process provides a better understanding of the spin-exchange optical pumping method that is used to polarize ¹²⁹-Xe, and it helps the optimization of mass production of hyperpolarized ¹²⁹-Xe. The second project of the research work involves the construction of a low readout field imaging system, which is capable of producing magnetic resonance images using both water and hyperpolarized ¹²⁹-Xe as imaging agents, under a low readout magnetic field, and is the first of its kind at room temperature.

Item Type:Thesis (Dissertation (Ph.D.))
Subject Keywords:hyperpolarized 129-Xe; MRI; spin-exchange optical pumping; spin-exchange rate constants
Degree Grantor:California Institute of Technology
Division:Physics, Mathematics and Astronomy
Major Option:Physics
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Hughes, Emlyn Willard
Thesis Committee:
  • Hughes, Emlyn Willard (chair)
  • Porter, Frank C.
  • Politzer, Hugh David
  • Eisenstein, James P.
Defense Date:17 May 2004
Record Number:CaltechETD:etd-05282004-132432
Persistent URL:
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:2190
Deposited By: Imported from ETD-db
Deposited On:28 May 2004
Last Modified:21 Jan 2021 23:36

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