Browse by Committee Member

A

Abernathy, Morgan Elizabeth (2022) Antibody Targeting of HIV-1 Env: a Structural Perspective. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/0p2b-aa45. https://resolver.caltech.edu/CaltechTHESIS:02012022-191225421

Aceves, Aiden Joseph (2022) Machine Learning and Modeling Methods for Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5j34-0d55. https://resolver.caltech.edu/CaltechTHESIS:09092021-024951318

Anaya, Michael Aurelio (2021) Modernization of Monoclonal Antibody Screening and Protein-interaction Assays. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xy05-bb64. https://resolver.caltech.edu/CaltechTHESIS:06072021-233800139

Arias, Renee Justine (2018) Examination of Selenium Incorporation and Product Formation in the Nitrogenase FeMo-Cofactor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/5WZV-R440. https://resolver.caltech.edu/CaltechTHESIS:05252018-140505343

Ahmed, Alysia Ashley (2015) Structural Characterization of Pro-inflammatory and Anti-inflammatory Immunoglobulin G Fc Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9GT5K33. https://resolver.caltech.edu/CaltechTHESIS:05292015-064617250

Anderson, Megan Jo (2009) Microfluidics-Based Strategies for Protein Crystallography. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/P5ZD-0S21. https://resolver.caltech.edu/CaltechETD:etd-10172008-222221

Ambroggio, Xavier Ignacio (2005) Structural and Functional Studies of Jamm Domain Proteins and Their Role in the Ubiquitin System. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EVW4-CC51. https://resolver.caltech.edu/CaltechETD:etd-09302004-090155

B

Blythe, Emily Elizabeth (2019) Characterization of Adaptor Binding and Substrate Processing by VCP/p97. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9K4M-0C48. https://resolver.caltech.edu/CaltechTHESIS:05222019-125958370

Berry, Alexandria Helen T. (2014) Designing Conformational Control of Human Tissue Transglutaminase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/WW1E-VT19. https://resolver.caltech.edu/CaltechTHESIS:02282014-131036761

Benjamin Schooler, Jordan (2006) Structural Studies of Human Immunodeficiency Virus Type I by CryoElectron Tomography. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HM3M-HZ81. https://resolver.caltech.edu/CaltechETD:etd-06052006-124843

Barbee, Susannah Dale (2005) The Functions of Phosphatidylinositol 3-Kinase in T Lymphocyte Development: Roles in Positive Selection and Thymic Exit. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3bbr-b515. https://resolver.caltech.edu/CaltechETD:etd-10062004-073848

Borths, Elizabeth Loraine (2005) Structural and Biochemical Characterization of the Vitamin B₁₂ ABC Transporter, BtuCD-F. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/kkkr-tk81. https://resolver.caltech.edu/CaltechETD:etd-01032005-142802

Bolon, Daniel N. (2002) Computational Enzyme Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/W7F3-DS14. https://resolver.caltech.edu/CaltechETD:etd-01252002-100801

C

Chuapoco, Miguel Roberto Estella (2023) Adeno-Associated Viral Vectors for Gene Delivery to the Non-Human Primate Brain. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/gngs-q727. https://resolver.caltech.edu/CaltechTHESIS:06012023-221050920

Cohen, Alexander Armand (2021) Developing Multivalent Nanoparticle Vaccines Against Current and Future Viruses. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/r33z-kj46. https://resolver.caltech.edu/CaltechTHESIS:06082021-015935441

Chitsaz, Mohsen (2014) Protein Structure Refinement Algorithms. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7731-QM74. https://resolver.caltech.edu/CaltechTHESIS:06072014-074257676

Choi, Eun Jung (2006) Development and Applications of Computational Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ZNED-BV38. https://resolver.caltech.edu/CaltechETD:etd-06012006-103350

Chi, Yong (2001) Negative Regulation of Transcription Factors by Srb10 Cyclin-Dependent Kinase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/tb1q-fz89. https://resolver.caltech.edu/CaltechTHESIS:03072014-113238525

D

Dam, Kim-Marie Anh (2023) Structural Insights into the Conformational Plasticity and Antibody Recognition of HIV-1 Env. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8pvb-dx31. https://resolver.caltech.edu/CaltechTHESIS:06022023-003659646

Ding, Xiaozhe (2023) Computation-Aided Protein Engineering for Targeted Therapeutic Delivery. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7n15-3076. https://resolver.caltech.edu/CaltechTHESIS:05052023-192721059

Dobro, Megan J. (2012) The Structural Biology of HIV Budding and Maturation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/X6XW-5303. https://resolver.caltech.edu/CaltechTHESIS:06012012-133153407

Detmer, Scott A. (2007) The Role of Mitofusin Proteins in Mitochondrial Fusion and Disease. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/7MXP-WS63. https://resolver.caltech.edu/CaltechETD:etd-04132007-181115

E

Esswein, Shannon Rose (2022) Structural Basis of Antibody Recognition of Viruses. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/krjp-se81. https://resolver.caltech.edu/CaltechTHESIS:05202022-005152490

Ewald, Andrew Josef (2003) The Molecular Control of Cell Movements during Early Vertebrate Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/67Z0-H535. https://resolver.caltech.edu/CaltechETD:etd-03312003-125746

F

Fry, Michelle Yen (2022) Mechanistic Studies of Tail-Anchored Membrane Protein Targeting to the ER. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/b3yj-c572. https://resolver.caltech.edu/CaltechTHESIS:08232021-203647268

G

Graumann, Johannes (2006) Implementation of Multidimensional Protein Identification Technology and its Application to the Characterization of Protein Complexes in Bakers Yeast. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/J3V1-QQ44. https://resolver.caltech.edu/CaltechETD:etd-05262006-095948

Green, Harry Miguel (2006) Novel Methods for Studying Ras/Erk MAP Kinase Signaling in Developing T Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8wa9-t690. https://resolver.caltech.edu/CaltechETD:etd-10242005-165226

Griffin, Erik Edmund (2006) Mechanisms of Mitochondrial Fusion and Fission. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/902F-8M09. https://resolver.caltech.edu/CaltechETD:etd-05242006-134647

Giannetti, Anthony Michael (2004) Biochemical, Biophysical, and Cellular Investigations of the Interactions of Transferrin Receptor with Transferrin and the Hereditary Hemochromatosis Protein, HFE. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/06QJ-JW93. https://resolver.caltech.edu/CaltechETD:etd-05262004-173612

H

Hoffmann, Magnus Adrian Gero (2022) Nanoparticle Technologies to Cure and Prevent Infectious Diseases. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/g0w1-rc77. https://resolver.caltech.edu/CaltechTHESIS:10302021-184745797

Herrera, Nadia (2017) Structure and Function of the Mycobacterial Mechanosensitive Channel of Large Conductance, MscL. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9JH3J77. https://resolver.caltech.edu/CaltechTHESIS:05162017-130844945

Hodas, Jennifer Jin Lee (2010) Elucidating the Hippocampal Dopaminergic Subproteome with Novel Bioorthogonal Techniques. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/DBGH-J143. https://resolver.caltech.edu/CaltechTHESIS:10012009-223603699

Henderson, Gregory Philip (2007) Ultrastructural Studies of Two Model Minimal Cells by Electron Cryotomography. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HK2B-CT58. https://resolver.caltech.edu/CaltechETD:etd-05142007-131453

Hansen, Carl Lars Genghis (2004) Microfluidic Technologies for Structural Biology. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/N9T3-7114. https://resolver.caltech.edu/CaltechETD:etd-06012004-144201

Huang, Po-Ssu (2004) Computational Design and Experimental Characterization of Protein Oligomers. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3DZW-2R54. https://resolver.caltech.edu/CaltechETD:etd-06012004-214823

Hamburger, Zsuzsa Andrea (2002) Crystallographic Studies of Invasin, a Bacterial Adhesion Molecule from Yersinia pseudotuberculosis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/NKAY-AB98. https://resolver.caltech.edu/CaltechETD:etd-06112002-135418

J

Jette, Claudia Angela (2022) Targeting Fusion Proteins of HIV-1 and SARS-CoV-2. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/pxa2-dy41. https://resolver.caltech.edu/CaltechThesis:04282022-192922044

Jonsson, Vanessa Danielle (2016) Robust Control of Evolutionary Dynamics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9NP22CH. https://resolver.caltech.edu/CaltechTHESIS:10132015-121212703

K

Kim, Jocelyn Tammy (2016) The Innate Immune System in Dendritic Cell-Targeted Lentiviral Vector Immunization and Cell-to-Cell Transmission of HIV-1. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z93N21CS. https://resolver.caltech.edu/CaltechTHESIS:06072016-121745268

Keeffe, Jennifer Rae (2009) Engineering Cyanovirin-N for Enhanced Viral Neutralization. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QSJH-5X56. https://resolver.caltech.edu/CaltechETD:etd-12232008-110031

Klein, Joshua Simon (2009) Investigations in the Design and Characterization of HIV-1 Neutralizing Molecules. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/QPEC-8Y25. https://resolver.caltech.edu/CaltechETD:etd-06042009-131723

Kwong, Gabriel Abner (2009) DNA Encoded Biotechnologies for Informative Cancer Diagnostics. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/AXMP-AM12. https://resolver.caltech.edu/CaltechETD:etd-06022009-172223

Kadaba, Neena Sujata (2008) Structural Studies of the E. coli Methionine ABC Transporter and Its Cognate Binding Protein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/3DRS-F441. https://resolver.caltech.edu/CaltechETD:etd-05052008-121818

Kielkopf, Clara Louise (2000) Structural Basis of DNA Recognition by Synthetic Ligands. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/73K1-K290. https://resolver.caltech.edu/CaltechTHESIS:03302018-093456214

L

Luebbert, Laura (2024) Complexity of Transcriptomic Data Analysis and Implications for Biological Discovery. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/xnw5-v914. https://resolver.caltech.edu/CaltechTHESIS:05042024-011724418

Lee, Sung-Eun Melanie (2013) Mechanism of Intestinal Colonization by Symbiotic Bacteria. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/24H5-8V73. https://resolver.caltech.edu/CaltechTHESIS:12122012-183251952

Luong, Tinh Nghi (2010) Signaling Proteins in the Post-Synaptic Density. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/GQ1D-CY75. https://resolver.caltech.edu/CaltechTHESIS:06012010-124413933

Lassila, Jonathan Kyle (2007) Methods for Computational Enzyme Design and Application to the Chorismate-Prephenate Rearrangement. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/4xm1-h147. https://resolver.caltech.edu/CaltechETD:etd-12182006-150535

Liu, Yang (2001) Molecular Mechanism of Sulfated Carbohydrate Recognition: Structural and Biochemical Studies of the Cysteine-Rich Domain of Mannose Receptor. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fj0v-hx76. https://resolver.caltech.edu/CaltechTHESIS:03102014-140846235

M

Maggiolo, Ailiena Okumura (2023) Crystallographic Studies of Nitrogenase. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p232-4w49. https://resolver.caltech.edu/CaltechTHESIS:06062023-051752771

Mock, Jee Young (2017) The Bag6 Complex: Biological Complexity through Modularity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z91C1TXQ. https://resolver.caltech.edu/CaltechTHESIS:06052017-184553539

Matzen, Kelly Jean (2012) Engineering of Dengue Virus Refractoriness in Aedes aegypti and Development of an Underdominant Gene Drive System in Drosophila melanogaster. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/YNFQ-WM56. https://resolver.caltech.edu/CaltechTHESIS:05192012-130917004

Medina-Marino, Andrew G. A. (2009) Construction and Initial Characterization of the Densin Knockout Mouse. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/HYHX-A061. https://resolver.caltech.edu/CaltechETD:etd-06022009-194041

Malasarn, Davin (2007) Molecular and Environmental Studies of Bacterial Arsenate Respiration. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/6PAA-PF90. https://resolver.caltech.edu/CaltechETD:etd-02232007-132917

Mosser, Eric Ardon (2007) Visualization of Cadherin-Cadherin Association in Living Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/1we9-7t88. https://resolver.caltech.edu/CaltechETD:etd-02142007-004140

Murphy, Gavin Erick (2007) Cryoelectron Tomography of Bacteria and their Macromolecular Machines. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/517B-0Z68. https://resolver.caltech.edu/CaltechETD:etd-05212007-162731

Martin, Warham Lance (2001) Protein-Protein Recognition: The Neonatal Fc Receptor and Immunoglobulin G. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9ek6-6833. https://resolver.caltech.edu/CaltechTHESIS:03072014-143524462

Morgan, Chantal Smith (2000) Full Sequence Design of an Alpha-Helical Protein and Investigation of the Importance of Helix Dipole and Capping Effects in Helical Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8wn3-cv27. https://resolver.caltech.edu/CaltechTHESIS:04092019-114920250

Meier, Joseph Thomas (1993) A Biological Arms Race: Site Specific DNA Recombination in Competing Immunofunctional Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/fd8q-cb34. https://resolver.caltech.edu/CaltechTHESIS:12262012-130125197

O

Orta, Anna Karen (2024) Leveraging the ΦX174 Protein Antibiotic to Study MraY Structure, Function, and Regulation. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/ggr0-0n72. https://resolver.caltech.edu/CaltechTHESIS:06042024-022255958

Owens, Gwen Ellen (2016) Biochemical and Biophysical Characterization of Huntingtin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9TM7835. https://resolver.caltech.edu/CaltechTHESIS:11042015-142900908

Olson, Clifford Anders (2008) mRNA Display Selection Using a Combinatorial 10FnIII Protein Library for Detection and Modulation of Cellular Processes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/9RCG-P320. https://resolver.caltech.edu/CaltechETD:etd-01082008-160438

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Quezada, Cindy María (2003) Histidine Phosphorylation in Bacterial Chemotaxis. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8DNJ-GX96. https://resolver.caltech.edu/CaltechETD:etd-05302003-145522

R

Rome, Michael Evan (2014) The Get3 ATPase Drives Unidirectional Targeting of Tail-Anchored Membrane Proteins. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9DZ068N. https://resolver.caltech.edu/CaltechTHESIS:04162014-173759568

Rao, Dinesh Subba (2010) Small RNAs Play Big Roles in Hematopoietic Development. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/D6GJ-4057. https://resolver.caltech.edu/CaltechTHESIS:05142010-184014918

Rice, Adrian Edward (2009) Biophysical and Cell Biological Studies Characterizing the Vertebrate Iron Exporter Ferroportin. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/2P16-3X70. https://resolver.caltech.edu/CaltechETD:etd-05192009-163326

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Schaus, Lucas Jean Nicolas (2025) Studies on Scaling Throughput in Protein Engineering. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/jqng-x012. https://resolver.caltech.edu/CaltechTHESIS:08022024-005547280

Stevens, Taylor Anthony (2024) Characterization of a Novel Membrane Protein Insertase in the Mitochondrial Outer Membrane. Dissertation (Ph.D.), California Institute of Technology. https://resolver.caltech.edu/CaltechTHESIS:12092023-142606831

Su, Tsu-Te Judith (2014) Label-free Detection of Single Molecule Using Microtoroid Optical Resonators. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/EHWP-DH17. https://resolver.caltech.edu/CaltechTHESIS:05302014-140200007

Suloway, Christian J. M. (2012) Structural Insights into Tail-Anchored Protein Targeting by Get3. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/AGES-WJ42. https://resolver.caltech.edu/CaltechTHESIS:02282012-151846967

Strop, Pavel (2002) Characterization of the Mechanosensitive Channel of Large Conductance. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nkqb-gd95. https://resolver.caltech.edu/CaltechETD:etd-05092002-155216

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Tesar, Devin Brent (2009) Investigations of the Mechanisms of Receptor-Mediated Immunoglobulin Transport in Mammals and Birds. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8M42-R866. https://resolver.caltech.edu/CaltechETD:etd-11122008-131536

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Vernooij, Bernardus Theodorus Maria (1992) The mouse T cell receptor gamma genes. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/wnmy-rm49. https://resolver.caltech.edu/CaltechTHESIS:09212011-131628448

W

Wang, Jingzhou (2021) CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p0kj-9d56. https://resolver.caltech.edu/CaltechTHESIS:05282021-080632319

Wang, Haoqing (2019) Structure and Dynamics of HIV-1 Env Trimer. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/65VD-VM42. https://resolver.caltech.edu/CaltechTHESIS:02272019-142326751

Wenke, Belinda B. (2019) The Many Roles of the Nitrogenase Iron Protein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/8RB1-HC30. https://resolver.caltech.edu/CaltechTHESIS:04222019-175445561

Wannier, Timothy Milton (2015) Computationally Guided Monomerization of Red Fluorescent Proteins of the Class Anthozoa. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9571908. https://resolver.caltech.edu/CaltechTHESIS:01272015-110638252

Wu, Yunji (2015) Structural Characterizations of the Dimeric Anti-HIV Antibody 2G12 and the HIV-2 Envelope Glycoprotein. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z98050K6. https://resolver.caltech.edu/CaltechTHESIS:05212015-194407438

Walkup, Ward Gale IV (2014) Biochemical Studies of Postsynaptic Density Signaling Proteins With a Focus on synGAP and PDZ Domains. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Z9N877R8. https://resolver.caltech.edu/CaltechTHESIS:12182013-191308687

Wade, Lawrence A. (2011) An Evanescent Perspective on Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/AGAJ-PE93. https://resolver.caltech.edu/CaltechTHESIS:09102010-145946974

Winblade, Natalie Dawn (2001) Blocking Adhesion to Cell and Tissue Surfaces via Steric Stabilization with Graft Copolymers Containing Poly(Ethylene Glycol) and Phenylboronic Acid. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/B47A-E319. https://resolver.caltech.edu/CaltechETD:etd-01202002-221541

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Yang, Zhi (2022) Conformational Plasticity of HIV-1 Env and Implications for Vaccine Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/99hp-y284. https://resolver.caltech.edu/CaltechTHESIS:01222022-001845303

Yu, Kenneth Kwok-Chang (2012) Engineering Immunity Against HIV. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/GFQ8-M763. https://resolver.caltech.edu/CaltechTHESIS:04162012-151100376

Yang, Fan (2011) Biochemical and Biophysical Characterizations of Immunoglobulin Superfamily Receptors Neogenin and L1. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/Q8ET-K632. https://resolver.caltech.edu/CaltechTHESIS:10242010-143824484

Yang, Lili (2004) Towards Engineering Immunity. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/XTDP-SC35. https://resolver.caltech.edu/CaltechETD:etd-06042004-000641

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Zhu, Ronghui (2023) Multicellular Circuit Design in Mammalian Cells. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/p0fn-qa56. https://resolver.caltech.edu/CaltechTHESIS:07252022-061122576

Zollars, Eric Stafford (2006) Force Field Development in Protein Design. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/55br-9a21. https://resolver.caltech.edu/CaltechETD:etd-06052006-155305