The Role of Fucose in Learning and Memory: the Identification of a Fucosylprotein, Synapsin I, in the Rat Brain and the Characterization of its Fucosylation

Citation

Luo, Wen-I (2004) The Role of Fucose in Learning and Memory: the Identification of a Fucosylprotein, Synapsin I, in the Rat Brain and the Characterization of its Fucosylation. Master's thesis, California Institute of Technology. doi:10.7907/P7ZV-C811. https://resolver.caltech.edu/CaltechTHESIS:04262013-154211086

Abstract

Previous studies have shown that the glycoproteins containing the fucose moiety are involved in neuronal communication phenomena such as long-term potentiation and memory formation. These results imply that fucose containing glycoproteins might play an important role in learning and memory. To understand the role of fucose in neuronal communication, and the mechanisms by which fucose may be involved in information storage, the identification of fucosylproteins is essential. This report describes the identification and characterization of fucosylproteins in the brain, which will provide new insights into the role of the fucose involved molecular interactions.

Thesis Files