Citation
Brady, William Thomas (1957) The Synthesis of O-Methyl-N-Acetyl-L-Tyrosine. Master's thesis, California Institute of Technology. doi:10.7907/2XEN-8E12. https://resolver.caltech.edu/CaltechTHESIS:04292010-095951946
Abstract
An efficient method of preparing N-acetyl-L-tyrosine methyl ester is described. This compound has been converted to the optically pure O-methyl derivative by reaction with diazomethane. The saponification of N-acetyl-L-tyrosine methyl ester is a more convenient rout to N-acetyl-L-tyrosine than the direct acetylation of L-tyrosine. N-acetyl-L-tyrosine can be converted to optically pure O-methylN-acetyl-L-tyrosine via the Williamson synthesis. The preparation of several other derivatives of L- tyrosine is also described.
| Item Type: | Thesis (Master's thesis) |
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| Subject Keywords: | (Chemistry) |
| Degree Grantor: | California Institute of Technology |
| Division: | Chemistry and Chemical Engineering |
| Major Option: | Chemistry |
| Thesis Availability: | Public (worldwide access) |
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| Thesis Committee: |
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| Defense Date: | 1 January 1957 |
| Record Number: | CaltechTHESIS:04292010-095951946 |
| Persistent URL: | https://resolver.caltech.edu/CaltechTHESIS:04292010-095951946 |
| DOI: | 10.7907/2XEN-8E12 |
| Default Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
| ID Code: | 5752 |
| Collection: | CaltechTHESIS |
| Deposited By: | Tony Diaz |
| Deposited On: | 07 Jul 2010 15:21 |
| Last Modified: | 15 Aug 2023 20:33 |
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