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An Ultracentrifugal Study of the Dissociation of Human Carboxyhemoglobin


Hutchinson, William Day (1957) An Ultracentrifugal Study of the Dissociation of Human Carboxyhemoglobin. Master's thesis, California Institute of Technology. doi:10.7907/W8JC-7T49.


The dissociation of human carboxyhemoglobin has been investigated by means of sedimentation velocity measurements. Sedimentation studies on this protein have been extended to concentrations as low as 0.002% by the use of absorption optics. Hemoglobin was observed to dissociate increasingly as the pH was changed from 7 to 5. Apparent dissociation constants at each pH have been calculated. Values of the apparent specific volume of human carboxyhemoglobin have been found.

Item Type:Thesis (Master's thesis)
Subject Keywords:Chemistry
Degree Grantor:California Institute of Technology
Division:Chemistry and Chemical Engineering
Major Option:Chemistry
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Vinograd, Jerome Rubin
Thesis Committee:
  • Unknown, Unknown
Defense Date:1 January 1957
Record Number:CaltechTHESIS:04262010-094002832
Persistent URL:
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:5742
Deposited By: Tony Diaz
Deposited On:28 Jun 2010 15:31
Last Modified:13 Oct 2023 19:40

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