Citation
Hurley, John Neal (1974) The Preparation and Properties of Large Lecithin Bilayer Vesicles. Master's thesis, California Institute of Technology. doi:10.7907/M7HY-MS72. https://resolver.caltech.edu/CaltechTHESIS:11132009-091109533
Abstract
Sonicated lecithin vesicles of an "average" diameter of 1200 Å were prepared. PMR studies show a higher phase transition temperature than that found for small (300 - 500 Å) vesicles. Osmotic pressure collapses the vesicle but does not change the PMR linewidth. This differs from the effect found in small vesicles. Upon addition of a cyclic polyether (cyclohexyl-15-crown-5) to a solution of large vesicles, the water diffusion rate is found to increase by a factor of 5 to 10. The internal water volume also increases significantly, suggesting that the crown compound is incorporated into the bilayer.
| Item Type: | Thesis (Master's thesis) |
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| Subject Keywords: | (Chemistry) |
| Degree Grantor: | California Institute of Technology |
| Division: | Chemistry and Chemical Engineering |
| Major Option: | Chemistry |
| Thesis Availability: | Public (worldwide access) |
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| Thesis Committee: |
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| Defense Date: | September 1973 |
| Record Number: | CaltechTHESIS:11132009-091109533 |
| Persistent URL: | https://resolver.caltech.edu/CaltechTHESIS:11132009-091109533 |
| DOI: | 10.7907/M7HY-MS72 |
| Default Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. |
| ID Code: | 5373 |
| Collection: | CaltechTHESIS |
| Deposited By: | Tony Diaz |
| Deposited On: | 17 Nov 2009 21:59 |
| Last Modified: | 26 Jul 2024 21:52 |
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