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Novel Reactivity and Applications of Transition Metal-Catalyzed Nucleophilic Substitution Reactions

Citation

Tong, Xiaoyu (2024) Novel Reactivity and Applications of Transition Metal-Catalyzed Nucleophilic Substitution Reactions. Dissertation (Ph.D.), California Institute of Technology. doi:10.7907/nqkk-2x98. https://resolver.caltech.edu/CaltechTHESIS:05152024-205420698

Abstract

For more than 20 years, the Fu lab has explored the use of transition metal catalysts to enable novel nucleophilic substitution reactions. However, deficiencies in both fundamental reactivity and useful applications persist in this area. The research detailed in this thesis focuses on the development of reactivity and applications of transition metal-catalyzed nucleophilic substitution reactions.

Item Type:Thesis (Dissertation (Ph.D.))
Subject Keywords:Organic, catalysis, cross-coupling
Degree Grantor:California Institute of Technology
Division:Chemistry and Chemical Engineering
Major Option:Chemistry
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Fu, Gregory C.
Thesis Committee:
  • Reisman, Sarah E.
  • Stoltz, Brian M. (chair)
  • Peters, Jonas C.
  • Fu, Gregory C.
Defense Date:15 May 2024
Funders:
Funding AgencyGrant Number
National Institute of General Medical Sciences (NIGMS)R01–GM62871
National Institute of General Medical Sciences (NIGMS)R35–GM145315
Record Number:CaltechTHESIS:05152024-205420698
Persistent URL:https://resolver.caltech.edu/CaltechTHESIS:05152024-205420698
DOI:10.7907/nqkk-2x98
Related URLs:
URLURL TypeDescription
https://doi.org/10.1021/jacs.2c06154DOIArticle adapted for ch.2
https://doi.org/10.1002/anie.202306663DOIArticle adapted for ch.4
ORCID:
AuthorORCID
Tong, Xiaoyu0000-0002-1343-6335
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:16385
Collection:CaltechTHESIS
Deposited By: Xiaoyu Tong
Deposited On:28 May 2024 17:55
Last Modified:28 May 2024 17:55

Thesis Files

[img] PDF (Redacted Thesis (ch.3 ch.5 omitted)) - Final Version
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