Citation
Chang, Daniel Kwon (2022) Nickel-Catalyzed Electroreductive Cross-Coupling Reactions of Anhydrides and Alkyl Halides. Master's thesis, California Institute of Technology. doi:10.7907/w0pr-fs28. https://resolver.caltech.edu/CaltechTHESIS:05122022-031448609
Abstract
The formation of new carbon–carbon bonds is one of the most important transformations in organic chemistry due to its ability to build the backbone of organic molecules. Nickel-catalyzed reductive cross-coupling reactions have recently emerged as an efficient and powerful strategy for the creation of new carbon–carbon bonds. Furthermore, electrochemistry can be harnessed to overcome some of the challenges encountered in many of the reductive cross-coupling reactions in the literature. Herein, we discuss the development of a new electroreductive nickel-catalyzed cross-coupling of anhydrides with unactivated alkyl bromides in collaboration with Amgen to produce large amounts of substituted cyclobutane products.
| Item Type: | Thesis (Master's thesis) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Subject Keywords: | Nickel, cross-coupling, electrochemistry | ||||||||
| Degree Grantor: | California Institute of Technology | ||||||||
| Division: | Chemistry and Chemical Engineering | ||||||||
| Major Option: | Chemistry | ||||||||
| Thesis Availability: | Not set | ||||||||
| Research Advisor(s): |
| ||||||||
| Thesis Committee: |
| ||||||||
| Defense Date: | 2022 | ||||||||
| Funders: |
| ||||||||
| Record Number: | CaltechTHESIS:05122022-031448609 | ||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechTHESIS:05122022-031448609 | ||||||||
| DOI: | 10.7907/w0pr-fs28 | ||||||||
| ORCID: |
| ||||||||
| Default Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||
| ID Code: | 14577 | ||||||||
| Collection: | CaltechTHESIS | ||||||||
| Deposited By: | Daniel Chang | ||||||||
| Deposited On: | 16 May 2022 18:04 | ||||||||
| Last Modified: | 13 Jul 2022 22:17 |
Full text not available from this repository.
Repository Staff Only: item control page
