Browse by Committee Member

2013

Zhang, Bin (2013) Sec-facilitated protein translocation and membrane integration. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:10172012-174905364

Daeffler, Christopher Scot (2013) Ring-opening metathesis of bulky norbornene monomers and the radical-mediated hydrophosphonation of olefins. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:03312013-175520336

Limapichat, Walrati (2013) Probing the roles of receptor structure, drug-receptor interactions, and receptor crosstalk in ligand-gated ion channel function. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:11052012-192506907

2012

Blum, Angela Patricia (2012) Structure-function studies of nicotinic acetylcholine receptors using unnatural amino acids and synthetic agonist analogs. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:11042011-173102026

Frazier, Shawnalea J. (2012) Optimization of the GluCl/IVM neuronal silencing tool via protein engineering. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:05252012-121406958

Kedrowski, Sean M. A. (2012) I. Chemical-Scale Studies of Ligand-Gated Ion Channels, and II. Novel Methods for Phosphonate Synthesis. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:10112011-135016656

Puskar, Nyssa Leigh (2012) Structure-function studies of nicotinic acetylcholine receptors using unnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:02172012-141718925

Thomas, Renee Michelle (2012) The design, synthesis, and application of ruthenium metathesis catalysts for the preparation of small molecules and polymers. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:05082012-070058810

2011

Muzikar, Katy Ann (2011) Repression of DNA-binding-dependent glucocorticoid receptor-mediated gene expression. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:12142010-165109760

Phillips, John W. (2011) Biological activity of a Py-Im polyamide androgen receptor antagonist. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:06022011-172257819

Shanata, Jai Anand Pattur (2011) Single-molecule studies of ion channels expressing unnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:06082011-080856211

2010

Farkas, Michelle E (2010) Structural variations on the turn unit of DNA-binding hairpin Py-Im polyamides. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:10192009-145249345

Neidholdt, Evan L. (2010) Novel pyroelectric and switched ferroelectric ion sources in mass spectrometry: implementation and applications. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:03292010-222225209

Puckett, Cindy Ann (2010) The cellular uptake of luminescent ruthenium complexes. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:01062010-122905478

Tai, Hwan-Ching (2010) Characterization of the brain proteasome and its interacting proteins and their regulation by neuronal activity. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:12092009-103613738

2009

Eastwood, Amy Lynn (2009) Investigating structure-function relationships in ion channels using unatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01062009-133603

Hanek, Ariele Patrice (2009) Chemical-scale investigations of cys-loop neurotransmitter gated ion channels. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05282009-112657

Knowles, Robert R (2009) Asymmetric organocatalysis in complex target synthesis: progress towards the total synthesis of diazonamide A. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10282008-080437

Murrey, Heather Elizabeth (2009) Identification and characterization of the plasticity-relevant fucose-alpha(1-2)galactose glycoproteome from mouse brain. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-12182008-145714

Privett, Heidi Kathleen (2009) An iterative approach to de novo computational enzyme design and the successful application to the Kemp elimination. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05272009-091024

Rodriguez, Erik Ali (2009) In Vivo Incorporation of Multiple Unnatural Amino Acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01122009-153110

Stockdill, Jennifer Lynn (2009) Forays into the synthesis of zoanthenol: intriguing patterns in reactivity and selectivity. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01022009-165956

Torrice, Michael McCann (2009) Chemical-scale studies of the nicotinic and muscarinic acetylcholine receptors. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-08072008-103726

Whited, Matthew Thomas (2009) Synthetic and mechanistic studies of small-molecule activation at low-valent iron, cobalt, and iridium centers. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05062009-173812

2008

Beatty, Kimberly Elizabeth (2008) Imaging the proteome : metabolic tagging of newly synthesized proteins with reactive methionine analogues. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-03052008-105142

Beeson, Teresa Diane (2008) Development of enantioselective organocatalytic technologies for the alpha-functionalization of aldehydes and ketones. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05262008-115504

Kadaba, Neena Sujata (2008) Structural studies of the E. coli methionine ABC transporter and its cognate binding protein. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05052008-121818

Kim, Hugh Inkon (2008) Fundamental and applied studies of the structures and reaction dynamics of biomolecules using mass spectrometry and ion mobility spectrometry. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05092008-165701

Otey, Christopher R (2008) Structural and functional exploration of an artificial family of cytochromes P450. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-06112008-094638

Shao, Fangwei (2008) DNA-mediated hole and electron transport. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-06282007-105808

Tsai, Sherry M (2008) Alpha-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10152007-175458

Xiu, Xinan (2008) Structure-function studies of nicotinic acetylcholine receptors using unnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-12142007-125144

2007

Berlin, Jacob Myar (2007) Design of olefin metathesis catalysts : from enantioselective reactions to tetrasubstituted olefins. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-02192007-153310

Funk, Timothy William (2007) Chemo- and stereoselective olefin metathesis in small molecule synthesis. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-06152006-110234

Goodwin, Nicole C (2007) Application of iminium activation technologies to natural product synthesis: Total syntheses of the spiculisporic acids, progress towards the total synthesis of cylindrocyclophane F, and a formal synthesis of cylindrocyclophane A. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-07242006-134454

Khidekel, Nelly (2007) A chemoenzymatic strategy toward understanding O-GlcNAc glycosylation in the brain. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-03022007-083916

Kwon, Inchan (2007) Protein engineering via site-specific incorporation of nonnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01222007-010333

Lamarre-Vincent, Nathan (2007) Identification and functional analysis of O-GlcNAc glycosylation on the transcription factor cAMP-response element binding protein. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05292007-183523

Lee, Lori WaiHang (2007) Chemical scale investigations of the gating mechanism of ion channels. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01152007-080704

Millward, Steven Wesley (2007) The design, synthesis, and evolution of macrocyclic mRNA display libraries containing unnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05142007-161158

Son, Soojin (2007) Biosynthetic approaches to protein engineering using fluorinated amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-09172008-144626

Zhang, Kechun (2007) Engineering protein-based materials through coiled-coil motifs. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01232007-144117

2006

Cashin, Amanda Leigh (2006) Chemical scale investigations of drug-receptor interactions at the nicotinic acetylcholine receptor. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-03022006-172355

Grimm, Ronald L. (2006) Fundamental studies of the mechanisms and applications of field-induced droplet ionization mass spectrometry and electrospray mass spectrometry. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10092005-222651

Larsen, Catharine Hoang-Mai (2006) Investigating imidazolidinone catalysts : enantioselective organocatalytic Diels–Alder reactions, conjugate additions to access non-natural alpha-amino acids, and bimodal catalyst activation for the development of organo-cascade reactions. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10142005-105810

Mock, Marissa Lee (2006) Protein modification through in vivo incorporation of noncanonical amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10252005-154242

Mu, Tingwei (2006) A chemical-scale study on the ligand-binding site of a serotonin-gated ion channel. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-08292005-210930

Spronk, Steven Adrian (2006) Investigations of ion channels with computational simulations and biochemical experiments. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-03132006-112152

Trend, Raissa M. (2006) Concerning the mechanism and selectivity of palladium(II)-catalyzed aerobic oxidation reactions. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-03202006-120555

2005

Beene, Darren Lee (2005) Chemical scale investigations of ligand-gated ion channels using unnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-04262005-153907

Brown, Sean Pomeroy (2005) Iminium and enamine activation: methods for enantioselective organocatalysis. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-02242005-174252

Fechter, Eric James (2005) Design of sequence-specific DNA intercalators. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-06052005-164552

Kapinus, Vadym (2005) Photophysical properties of protonated aromatic hydrocarbons. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01252005-123917

Northrup, Alan Bowers (2005) Design and development of new enantioselective organocatalytic transformations, a two-step synthesis of carbohydrates and progress toward the total synthesis of callipeltoside C. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-09242004-095741

Petersson, Ernest James (2005) Investigations of ion channel structure and function. I. Studies of nicotine binding to the acetylcholine receptor. II. Development of tools for studying learning and memory with unnatural amino acids. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05242005-172213

Rutenberg, Isaac Michael (2005) Functionalized polymers and surfaces via ring-opening metathesis polymerization. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-08132004-132724

Shapovalov, George G. (2005) Mechanosensitive channels of bacteria: structure and function. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-12122004-215151

2004

Carrico, Isaac Sheridan (2004) Protein engineering through in vivo incorporation of phenylalanine analogs. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-09082003-110526

Elmore, Donald Eugene (2004) Investigations of ion channel structure-function relationships using molecular modeling and experimental biochemistry. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05212004-144036

Jen, Wendy S. (2004) Development of new asymmetric organocatalytic methods and progress towards the total synthesis of guanacastepene A. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10282003-135857

Monahan, Sarah Lynn (2004) Site-specific incorporation of unnatural amino acids into receptors expressed in mammalian cells. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-05252004-153512

Starck, Shelley Ruth (2004) Exploring the proteome: insights into eukaryotic protein synthesis using puromycin analogs. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-06012004-235945

Zacharias, Niki Marie (2004) Chemical-scale manipulation of ion channels: in vivo nonsense suppression and targeted disulfide crosslinking. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01042004-210542

2003

Brandt, Gabriel Shaw (2003) Site-specific incorporation of synthetic amino acids into functioning ion channels. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-01202003-221429

Julian, Ryan R (2003) Molecular recognition of biomolecules in the gas phase. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-04292003-134947

Li, Lintong (2003) The tethered agonist approach to mapping ion-channel proteins: toward a structural model for the agonist-binding site of the nicotinic acetylcholine receptor. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-07312002-120928

Maurer, Joshua Ahab (2003) I. Structure-function analysis of the mechanosensitive channel of large conductance. II. Design of novel magnetic materials using crystal engineering. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10202002-002307

2002

Tang, Yi (2002) Protein engineering using unnatural amino acids : incorporation of leucine analogs into recombinant protein in vivo. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-08152006-084149

Yoon, Tehshik Peter (2002) The acyl-Claisen rearrangement: development of a novel metal-catalyzed Claisen rearrangement and enanitoselective variants of the acyl-Claisen rearrangement. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:01282010-153053761

2001

Debe, Derek A. (2001) Shaving levinthal with Occam's Razor : Understanding the rate limiting step in protein folding. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:11122009-154318044

1995

Benedicto, Alto D. (1995) Rational approaches to regulating polymer properties in ring-opening metathesis polymerization. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-09112007-131436

Fraley, Mark E. (1995) Synthesis of (+)-dynemicin A and analogs of wide structural variability. Establishment of the absolute configuration of natural dynemicin A. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10022007-135120

1994

Beal, Peter A. (1994) Recognition of double helical DNA by purine oligonucleotides via triple helix formation. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:04252013-080541344

Wu, Zhe (1994) Transition metal carbenes : controlled ring-opening metathesis polymerizations and metathetical reactions with acyclic olefins. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-08162006-082323

1988

Baker, Brenda Faye (1988) Sequence specific cleavage of double helical DNA N-bromoacetyldistamycin. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:01222013-095919666

Swager, Timothy Manning (1988) Precursor routes to conducting polymers from the ring-opening metathesis polymerization of cyclic olefins. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-08152005-160834