Wallace, Frederic A. (1960) pH titration studies of the acid denaturation of calf thymus deoxyribosenucleic acid. Master's thesis, California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:04212010-142614826
The acid denaturation of calf thymus deoxyribosenucleic acid (DNA) has been studied both by PH and spectrophotometric titration in the temperature range 10 - 30°C and at ionic strengths 0.1 F and 0.5 F. The number of hydrogen ions bound by the DNA at any given pH increased with increasing temperature and decreased with increasing ionic strength. The number bound at any given pH was greater after denaturation. A model for acid denaturation is proposed. The site of protonation of cytosine is discussed.
|Item Type:||Thesis (Master's thesis)|
|Degree Grantor:||California Institute of Technology|
|Division:||Chemistry and Chemical Engineering|
|Thesis Availability:||Public (worldwide access)|
|Defense Date:||1 January 1960|
|Default Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||21 Jun 2010 18:24|
|Last Modified:||26 Dec 2012 03:24|
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