Nesbitt, Stephen L. (1977) Thiosilanes as thioketalization reagents. Master's thesis, California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:04062010-085409602
Thiosilanes react efficiently with simple aldehydes and ketones when catalyzed with ZnI_2 to produce thioacetals and thioketals. Steroidal diketones were thioketalized with yields and selectivity superior to other methods when allowed to react with thiosilanes and ZnI_2. The overall thioketalization process proceeds through silyl-hemithioketal intermediates which can be detected and isolated from the reaction mixtures. The isolated silylhemithioketals can be resubmitted to the thioketalization reaction conditions and be converted to thioketals.
|Item Type:||Thesis (Master's thesis)|
|Degree Grantor:||California Institute of Technology|
|Division:||Chemistry and Chemical Engineering|
|Thesis Availability:||Public (worldwide access)|
|Defense Date:||21 October 1976|
|Default Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||19 Apr 2010 17:44|
|Last Modified:||26 Dec 2012 03:24|
- Final Version
See Usage Policy.
Repository Staff Only: item control page