A Caltech Library Service

Thiosilanes as thioketalization reagents


Nesbitt, Stephen L. (1977) Thiosilanes as thioketalization reagents. Master's thesis, California Institute of Technology.


Thiosilanes react efficiently with simple aldehydes and ketones when catalyzed with ZnI_2 to produce thioacetals and thioketals. Steroidal diketones were thioketalized with yields and selectivity superior to other methods when allowed to react with thiosilanes and ZnI_2. The overall thioketalization process proceeds through silyl-hemithioketal intermediates which can be detected and isolated from the reaction mixtures. The isolated silylhemithioketals can be resubmitted to the thioketalization reaction conditions and be converted to thioketals.

Item Type:Thesis (Master's thesis)
Subject Keywords:Chemistry
Degree Grantor:California Institute of Technology
Division:Chemistry and Chemical Engineering
Major Option:Chemistry
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Evans, David A.
Thesis Committee:
  • Unknown, Unknown
Defense Date:21 October 1976
Record Number:CaltechTHESIS:04062010-085409602
Persistent URL:
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:5692
Deposited By: Tony Diaz
Deposited On:19 Apr 2010 17:44
Last Modified:26 Dec 2012 03:24

Thesis Files

PDF - Final Version
See Usage Policy.


Repository Staff Only: item control page