Hurley, John N. (1974) The preparation and properties of large lecithin bilayer vesicles. Master's thesis, California Institute of Technology. http://resolver.caltech.edu/CaltechTHESIS:11132009-091109533
Sonicated lecithin vesicles of an "average" diameter of 1200 Å were prepared. PMR studies show a higher phase transition temperature than that found for small (300 - 500 Å) vesicles. Osmotic pressure collapses the vesicle but does not change the PMR linewidth. This differs from the effect found in small vesicles. Upon addition of a cyclic polyether (cyclohexyl-15-crown-5) to a solution of large vesicles, the water diffusion rate is found to increase by a factor of 5 to 10. The internal water volume also increases significantly, suggesting that the crown compound is incorporated into the bilayer.
|Item Type:||Thesis (Master's thesis)|
|Degree Grantor:||California Institute of Technology|
|Division:||Chemistry and Chemical Engineering|
|Thesis Availability:||Public (worldwide access)|
|Defense Date:||September 1973|
|Default Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Tony Diaz|
|Deposited On:||17 Nov 2009 21:59|
|Last Modified:||26 Dec 2012 03:18|
- Final Version
See Usage Policy.
Repository Staff Only: item control page