Hinton, Claude Willey (1954) The behavior of an unstable ring chromosome in Drosophila melanogaster. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-12152003-115148
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The behavior of "Catcheside's ring," an unstable closed-X chromosome [...] of Drosophila melanogaster, has been analyzed with the purpose of identifying the factors controlling the variable-level of [...] instability and of determining the mechanism of [...] elimination. The Y chromosome and the structure of the homologous rod-X chromosome were shown to have no influence on the frequency of [...] elimination. Since no segregating autosomal or sex-linked modifiers could be detected, the primary control of [...] instability must be limited to the [...] chromosome itself. The behavior of unstable small duplications derive from the [...] chromosome suggests that the locus of [...] instability must be in or near the [...] centromere region.
The frequency of [...] elimination is directly related to developmental temperature and to age of maternal [...] parents. Certain preliminary results incurred the speculation that a cytoplasmic factor is operative in [...] elimination.
Either anaphase lagging or the production of anaphase bridges by the [...] chromosome will account for its loss. The occurrence of [...] derivatives, deficient for either extensive or small euchromatic segments, suggests that anaphase bridges composed of continuous dicentric rings may be formed; however, such bridges do not necessarily constitute the exclusive means of elimination.
|Item Type:||Thesis (Dissertation (Ph.D.))|
|Degree Grantor:||California Institute of Technology|
|Thesis Availability:||Public (worldwide access)|
|Defense Date:||1 January 1954|
|Default Usage Policy:||No commercial reproduction, distribution, display or performance rights in this work are provided.|
|Deposited By:||Imported from ETD-db|
|Deposited On:||17 Dec 2003|
|Last Modified:||26 Dec 2012 03:13|
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