CaltechTHESIS
  A Caltech Library Service

Part I. Alpha-secondary isotope effects on the reaction catalyzed by fumarase; Part II. Salt effects on fumarase

Citation

Schmidt, Donald Emil (1967) Part I. Alpha-secondary isotope effects on the reaction catalyzed by fumarase; Part II. Salt effects on fumarase. Dissertation (Ph.D.), California Institute of Technology. http://resolver.caltech.edu/CaltechETD:etd-10042002-125501

Abstract

NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document. PART I The [alpha]-secondary isotope effect of L-malic-2-T-1, 4-C[superscript 14] acid on the reaction catalyzed by fumarase was determined. Evidence was presented which indicated that the reaction proceeded by formation of a carbonium ion in a rate-determining state at C-2 which possesses little sp[superscript 2] character. PART II The effects of sodium bromide and sodium phosphate at pH 7.3 and 27[degrees] were determined. A partial kinetic and mechanistic scheme has been developed to explain these effects.

Item Type:Thesis (Dissertation (Ph.D.))
Degree Grantor:California Institute of Technology
Division:Chemistry and Chemical Engineering
Major Option:Chemistry
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Richards, John H.
Thesis Committee:
  • Unknown, Unknown
Defense Date:21 March 1967
Record Number:CaltechETD:etd-10042002-125501
Persistent URL:http://resolver.caltech.edu/CaltechETD:etd-10042002-125501
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:3894
Collection:CaltechTHESIS
Deposited By: Imported from ETD-db
Deposited On:04 Oct 2002
Last Modified:26 Dec 2012 03:03

Thesis Files

[img]
Preview
PDF (Schmidt,jr_de_1967.pdf) - Final Version
See Usage Policy.

5Mb

Repository Staff Only: item control page