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Heterocaryosis in Neurospora crassa


Holloway, Bruce William (1953) Heterocaryosis in Neurospora crassa. Dissertation (Ph.D.), California Institute of Technology.


It has been shown that heterocaryon formation between certain biochemical mutants of Neurospora crassa is controlled by a number of genes apart from the biochemical mutant genes concerned. Genetic control of heterocaryosis has been shown for several different combinations of mutants. A detailed investigation of the heterocaryon formed between a mutant requiring pantothenic acid and one requiring lysine has demonstrated four and possibly five genes to be concerned in the process of heterocaryon formation. These genes may not only prevent the formation of a heterocaryon but also modify the type of heterocaryotic growth. The characters so affected are the time at which heterocaryotic growth commences, the ability to maintain heterocaryotic growth and the vigor of the growth. The possible mode of action of such genes has been discussed.

Item Type:Thesis (Dissertation (Ph.D.))
Degree Grantor:California Institute of Technology
Major Option:Biology
Thesis Availability:Public (worldwide access)
Research Advisor(s):
  • Unknown, Unknown
Thesis Committee:
  • Unknown, Unknown
Defense Date:1 January 1953
Record Number:CaltechETD:etd-04232003-113543
Persistent URL:
Default Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:1467
Deposited By: Imported from ETD-db
Deposited On:23 Apr 2003
Last Modified:26 Dec 2012 02:38

Thesis Files

PDF (Holloway_bw_1953.pdf) - Final Version
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